Ambika Verma
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Explore the profile of Ambika Verma including associated specialties, affiliations and a list of published articles.
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14
Citations
101
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Recent Articles
11.
Oh C, Li L, Verma A, Reuven A, Miao E, Bliska J, et al.
Cell Rep
. 2022 Nov;
41(8):111688.
PMID: 36417874
In neutrophils, caspase-11 cleaves gasdermin D (GSDMD), causing pyroptosis to clear cytosol-invasive bacteria. In contrast, caspase-1 also cleaves GSDMD but seems to not cause pyroptosis. Here, we show that this...
12.
Patyal P, Nguyen B, Zhang X, Azhar G, Ameer F, Verma A, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232837
CCG-1423 is a Rho A pathway inhibitor that has been reported to inhibit Rho/SRF-mediated transcriptional regulation. Serum response factor and its cofactors, which include ternary complex factors and myocardin-related transcription...
13.
Oh C, Verma A, Hafeez M, Hogland B, Aachoui Y
iScience
. 2021 Aug;
24(8):102910.
PMID: 34409271
, a cytosol-invasive gram-negative pathogen, deploys an array of type III-secreted effector proteins to evade host cell defenses. Caspase-11 and its human ortholog caspase-4 detect cytosolic lipopolysaccharide (LPS) and trigger...
14.
Oh C, Verma A, Aachoui Y
Front Immunol
. 2020 Sep;
11:1895.
PMID: 32973786
The airway epithelium and underlying innate immune cells comprise the first line of host defense in the lung. They recognize pathogen-associated molecular patterns (PAMPs) using membrane-bound receptors, as well as...
15.
Kovacs S, Oh C, Maltez V, McGlaughon B, Verma A, Miao E, et al.
Cell Rep
. 2020 Jul;
32(4):107967.
PMID: 32726630
Either caspase-1 or caspase-11 can cleave gasdermin D to cause pyroptosis, eliminating intracellular replication niches. We previously showed that macrophages detect Burkholderia thailandensis via NLRC4, triggering the release of interleukin...