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Amber D Bledsoe

Explore the profile of Amber D Bledsoe including associated specialties, affiliations and a list of published articles. Areas
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Citations 301
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Recent Articles
1.
Lewis M, Blain G, Hart C, Layec G, Rossman M, Park S, et al.
Am J Physiol Regul Integr Comp Physiol . 2021 Sep; 321(5):R687-R698. PMID: 34549627
Recently it was documented that fatiguing, high-intensity exercise resulted in a significant attenuation in maximal skeletal muscle mitochondrial respiratory capacity, potentially due to the intramuscular metabolic perturbation elicited by such...
2.
Trinity J, Kwon O, Broxterman R, Gifford J, Kithas A, Hydren J, et al.
Am J Physiol Heart Circ Physiol . 2020 Dec; 320(2):H668-H678. PMID: 33306447
Passive leg movement (PLM) evokes a robust and predominantly nitric oxide (NO)-mediated increase in blood flow that declines with age and disease. Consequently, PLM is becoming increasingly accepted as a...
3.
Kithas A, Broxterman R, Trinity J, Gifford J, Kwon O, Hydren J, et al.
Nitric Oxide . 2020 Sep; 104-105:51-60. PMID: 32979497
Nitric oxide synthase (NOS) inhibition with N(G)-monomethyl-l-arginine (L-NMMA) is often used to assess the role of NO in human cardiovascular function. However, the window of effect for L-NMMA on human...
4.
Wan H, Weavil J, Thurston T, Georgescu V, Bledsoe A, Jessop J, et al.
J Appl Physiol (1985) . 2020 Aug; 129(4):691-700. PMID: 32816637
We examined the interactive influence of the muscle reflex (MR) and the chemoreflex (CR) on the ventilatory response to exercise. Eleven healthy subjects (5 women/6 men) completed three bouts of...
5.
Wan H, Weavil J, Thurston T, Georgescu V, Hureau T, Bledsoe A, et al.
J Physiol . 2020 Mar; 598(12):2311-2321. PMID: 32170732
Key Points: Although the exercise pressor reflex (EPR) and the chemoreflex (CR) are recognized for their sympathoexcitatory effect, the cardiovascular implication of their interaction remains elusive. We quantified the individual...
6.
Craig J, Broxterman R, LA Salle D, Cerbie J, Ratchford S, Gifford J, et al.
J Physiol . 2019 Nov; 598(1):71-84. PMID: 31705661
Key Points: Exercise in patients with hypertension can be accompanied by an abnormal cardiovascular response that includes attenuated blood flow and an augmented pressor response. Endothelin-1, a very potent vasoconstrictor,...
7.
Sidhu S, Weavil J, Rossman M, Jessop J, Bledsoe A, Buys M, et al.
Hypertension . 2019 Oct; 74(6):1468-1475. PMID: 31607174
We investigated the impact of hypertension on circulatory responses to exercise and the role of the exercise pressor reflex in determining the cardiovascular abnormalities characterizing patients with hypertension. After a...
8.
Broxterman R, Layec G, Hureau T, Morgan D, Bledsoe A, Jessop J, et al.
Med Sci Sports Exerc . 2018 Jul; 50(8):1719. PMID: 30005058
No abstract available.
9.
Broxterman R, Hureau T, Layec G, Morgan D, Bledsoe A, Jessop J, et al.
J Physiol . 2018 Apr; 596(12):2301-2314. PMID: 29644702
Key Points: This investigation assessed the influence of group III/IV muscle afferents on small muscle mass exercise performance from a skeletal muscle bioenergetics perspective. Group III/IV muscle afferent feedback was...
10.
Hureau T, Weavil J, Thurston T, Broxterman R, Nelson A, Bledsoe A, et al.
J Physiol . 2018 Feb; 596(8):1373-1384. PMID: 29388218
Key Points: We investigated the contribution of group III/IV muscle afferents to carotid baroreflex resetting during electrically evoked (no central command) and voluntary (requiring central command) isometric knee extension exercise....