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Amanda Maffa

Explore the profile of Amanda Maffa including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 359
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Recent Articles
1.
Lam F, Morton S, Wyckoff J, Vu Han T, Hwang M, Maffa A, et al.
Nat Commun . 2018 May; 9(1):1991. PMID: 29777137
Effective treatment for glioblastoma (GBM) is limited by the presence of the blood-brain barrier (BBB) and rapid resistance to single agent therapies. To address these issues, we developed a transferrin-functionalized...
2.
Leung W, Shaffer C, Reed L, Smith S, Barshop W, Dirkes W, et al.
G3 (Bethesda) . 2015 Mar; 5(5):719-40. PMID: 25740935
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties...
3.
Floyd S, Pacold M, Huang Q, Clarke S, Lam F, Cannell I, et al.
Nature . 2013 Jun; 498(7453):246-50. PMID: 23728299
DNA damage activates a signalling network that blocks cell-cycle progression, recruits DNA repair factors and/or triggers senescence or programmed cell death. Alterations in chromatin structure are implicated in the initiation...