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Amanda Jane Leach

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Recent Articles
1.
Leach A, Wilson N, Arrowsmith B, Beissbarth J, Mulholland K, Santosham M, et al.
PLoS Med . 2024 Jun; 21(6):e1004375. PMID: 38829821
Background: In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and poor school performance, compared to those with normal...
2.
Su J, Leach A, Cass A, Morris P, Kong K
BMC Health Serv Res . 2023 Nov; 23(1):1186. PMID: 37907905
Background: In the Northern Territory (NT) the prevalence of otitis media (OM) in young Aboriginal children living in remote communities has persisted at around 90% over the last few decades....
3.
Kaspar A, Leach A
Public Health Pract (Oxf) . 2022 Sep; 1:100048. PMID: 36101696
Aim: Australian Aboriginal and Torres Strait Islander children have among the highest rates of otitis media (OM) and associated conductive hearing loss in the world. OM begins early in life...
4.
Leach A, Wilson N, Arrowsmith B, Beissbarth J, Mulholland E, Santosham M, et al.
Lancet Infect Dis . 2022 Jun; 22(9):1374-1387. PMID: 35772449
Background: Australian First Nations children are at very high risk of early, recurrent, and persistent bacterial otitis media and respiratory tract infection. With the PREVIX randomised controlled trials, we aimed...
5.
Abbott P, Askew D, Watego C, Hu W, Campbell L, Tyson C, et al.
BMJ Open . 2021 Dec; 11(12):e050839. PMID: 34952874
Objective: To better understand how to undertake valuable, ethical and sustainable randomised controlled clinical trial (RCT) research within Aboriginal and Torres Strait Islander primary health services. Design: In a qualitative...
6.
Kong K, Cass A, Leach A, Morris P, Kimber A, Su J, et al.
Trials . 2021 Jun; 22(1):403. PMID: 34134736
Background: Almost all Aboriginal children in remote communities have persistent bilateral otitis media affecting hearing and learning throughout early childhood and school years, with consequences for social and educational outcomes,...
7.
Leach A, Mulholland E, Santosham M, Torzillo P, McIntyre P, Smith-Vaughan H, et al.
BMC Pediatr . 2021 Mar; 21(1):117. PMID: 33685411
Background: Aboriginal children living in Australian remote communities are at high risk of early and persistent otitis media, hearing loss, and social disadvantage. Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi)...
8.
Leach A, Mulholland E, Santosham M, Torzillo P, McIntyre P, Smith-Vaughan H, et al.
Vaccine X . 2021 Mar; 7:100086. PMID: 33681756
Background: Aboriginal children living in remote communities are at high risk of early and persistent otitis media. and non-typeable (NTHi) are primary pathogens. Vaccines with potential to prevent early OM...
9.
Su J, Guthridge S, He V, Howard D, Leach A
BMC Public Health . 2020 Oct; 20(1):1521. PMID: 33028291
Background: The prevalence of otitis media (OM) and related hearing loss has remained persistently high among some groups of Australian Aboriginal children who are also reported to have poor academic...
10.
Oguoma V, Wilson N, Mulholland K, Santosham M, Torzillo P, McIntyre P, et al.
BMJ Open . 2020 May; 10(5):e033511. PMID: 32448790
Introduction: and non-typeable (NTHi) are major otitis media pathogens that densely co-colonise the nasopharynx and infect the middle ear of Australian Aboriginal infants from very early in life. Our co-primary...