Amanda Ferdinand
Overview
Explore the profile of Amanda Ferdinand including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
161
Followers
0
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Recent Articles
1.
Stockley M, Benedetti G, Blencowe P, Boulton S, Boyd S, Calder M, et al.
J Med Chem
. 2023 Feb;
PMID: 36815444
No abstract available.
2.
Stockley M, Ferdinand A, Benedetti G, Blencowe P, Boyd S, Calder M, et al.
J Med Chem
. 2022 Oct;
65(20):13879-13891.
PMID: 36200480
Human DNA polymerase theta (Polθ), which is essential for microhomology-mediated DNA double strand break repair, has been proposed as an attractive target for the treatment of BRCA deficient and other...
3.
Zatreanu D, Robinson H, Alkhatib O, Boursier M, Finch H, Geo L, et al.
Nat Commun
. 2021 Jun;
12(1):3636.
PMID: 34140467
To identify approaches to target DNA repair vulnerabilities in cancer, we discovered nanomolar potent, selective, low molecular weight (MW), allosteric inhibitors of the polymerase function of DNA polymerase Polθ, including...