Amal Houssaini
Overview
Explore the profile of Amal Houssaini including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
978
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Recent Articles
1.
Born E, Lipskaia L, Breau M, Houssaini A, Beaulieu D, Marcos E, et al.
Circulation
. 2022 Dec;
147(8):650-666.
PMID: 36515093
Background: Senescent cells (SCs) are involved in proliferative disorders, but their role in pulmonary hypertension remains undefined. We investigated SCs in patients with pulmonary arterial hypertension and the role of...
2.
Beaulieu D, Attwe A, Breau M, Lipskaia L, Marcos E, Born E, et al.
Eur Respir J
. 2021 Jan;
58(2).
PMID: 33509955
Background: Cell senescence is a key process in age-associated dysfunction and diseases, notably chronic obstructive pulmonary disease (COPD). We previously identified phospholipase A2 receptor 1 (PLA2R1) as a positive regulator...
3.
Adnot S, Breau M, Houssaini A
Am J Respir Cell Mol Biol
. 2019 Oct;
62(3):271-272.
PMID: 31622556
No abstract available.
4.
Breau M, Houssaini A, Lipskaia L, Abid S, Born E, Marcos E, et al.
JCI Insight
. 2019 Oct;
4(19).
PMID: 31578304
Oxidative stress is a major contributor to chronic lung diseases. Antioxidants such as N-acetylcysteine (NAC) are broadly viewed as protective molecules that prevent the mutagenic effects of reactive oxygen species....
5.
Abid S, Marcos E, Parpaleix A, Amsellem V, Breau M, Houssaini A, et al.
Eur Respir J
. 2019 Jul;
54(4).
PMID: 31320454
Macrophages are major players in the pathogenesis of pulmonary arterial hypertension (PAH).To investigate whether lung macrophages and pulmonary-artery smooth muscle cells (PASMCs) collaborate to stimulate PASMC growth and whether the...
6.
Mougenot N, Mika D, Czibik G, Marcos E, Abid S, Houssaini A, et al.
Cardiovasc Res
. 2019 Jan;
115(12):1778-1790.
PMID: 30605506
Aims: Increase of cardiac cAMP bioavailability and PKA activity through adenylyl-cyclase 8 (AC8) overexpression enhances contractile function in young transgenic mice (AC8TG). Ageing is associated with decline of cardiac contraction...
7.
Abid S, Kebe K, Houssaini A, Tomberli F, Marcos E, Bizard E, et al.
J Cardiovasc Pharmacol
. 2018 Feb;
71(5):283-292.
PMID: 29438213
Nitric oxide (NO) donors may be useful for treating pulmonary hypertension (PH) complicating sickle cell disease (SCD), as endogenous NO is inactivated by hemoglobin released by intravascular hemolysis. Here, we...
8.
Houssaini A, Breau M, Kebe K, Abid S, Marcos E, Lipskaia L, et al.
JCI Insight
. 2018 Feb;
3(3).
PMID: 29415880
Chronic obstructive pulmonary disease (COPD) is a highly prevalent and devastating condition for which no curative treatment is available. Exaggerated lung cell senescence may be a major pathogenic factor. Here,...
9.
Houssaini A, Adnot S
Am J Respir Cell Mol Biol
. 2017 Nov;
57(5):509-511.
PMID: 29090958
No abstract available.
10.
Saker M, Lipskaia L, Marcos E, Abid S, Parpaleix A, Houssaini A, et al.
Arterioscler Thromb Vasc Biol
. 2016 Jul;
36(9):1879-90.
PMID: 27444202
Objective: Senescent pulmonary artery smooth muscle cells (PA-SMCs) may contribute to the pathogenesis of pulmonary hypertension by producing secreted factors. The aim of this study was to explore the role...