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Amada D Caliz

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Articles 8
Citations 43
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Recent Articles
1.
Craige S, Kaur G, Bond J, Caliz A, Kant S, Keaney Jr J
Antioxid Redox Signal . 2024 Aug; PMID: 39213161
Endothelial cells (ECs) line the entire vasculature system and serve as both barriers and facilitators of intra- and interorgan communication. Positioned to rapidly sense internal and external stressors, ECs dynamically...
2.
Kumari A, Caliz A, Yoo H, Kant S, Vertii A
Cytoskeleton (Hoboken) . 2024 May; 81(11):639-647. PMID: 38767050
The primary cilium is a characteristic feature of most non-immune cells and functions as an environmental signal transduction sensor. The defects in primary cilium have profound effects on the developmental...
3.
Liu H, Caliz A, Learnard H, Koupenova M, Keaney J, Kant S, et al.
bioRxiv . 2023 Oct; PMID: 37905100
Inflammatory stresses underlie endothelial dysfunction and contribute to the development of chronic cardiovascular disorders such as atherosclerosis and vascular fibrosis. The initial transcriptional response of endothelial cells to pro-inflammatory cytokines...
4.
Caliz A, Vertii A, Fisch V, Yoon S, Yoo H, Keaney Jr J, et al.
Front Cell Dev Biol . 2022 Nov; 10:979673. PMID: 36340039
Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. In the human body, MKK7 controls essential physiological processes, including but not limited...
5.
Kant S, Tran K, Kvandova M, Caliz A, Yoo H, Learnard H, et al.
Arterioscler Thromb Vasc Biol . 2021 Nov; 42(1):19-34. PMID: 34789002
Objective: Fluid shear stress (FSS) is known to mediate multiple phenotypic changes in the endothelium. Laminar FSS (undisturbed flow) is known to promote endothelial alignment to flow, which is key...
6.
Caliz A, Yoo H, Vertii A, Dolan A, Tournier C, Davis R, et al.
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502275
Mitogen kinase kinase 4 (MKK4) and mitogen kinase kinase 7 (MKK7) are members of the MAP2K family that can activate downstream mitogen-activated protein kinases (MAPKs). MKK4 has been implicated in...
7.
Specht K, Kant S, Addington A, McMillan R, Hulver M, Learnard H, et al.
Mol Metab . 2021 Jan; 45:101160. PMID: 33400973
Objective: The immediate signals that couple exercise to metabolic adaptations are incompletely understood. Nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) produces reactive oxygen species (ROS) and plays a significant role...
8.
Kant S, Craige S, Chen K, Reif M, Learnard H, Kelly M, et al.
Nat Commun . 2019 Sep; 10(1):4223. PMID: 31530804
Diseases related to impaired blood flow such as peripheral artery disease (PAD) impact nearly 10 million people in the United States alone, yet patients with clinical manifestations of PAD (e.g.,...