Alva Abrahamsson
Overview
Explore the profile of Alva Abrahamsson including associated specialties, affiliations and a list of published articles.
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4
Citations
7
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Recent Articles
1.
Golebiewska-Pikula J, Abrahamsson A, Chorell E
Bioorg Chem
. 2025 Feb;
157:108259.
PMID: 39952062
The continued advancement of oligonucleotide-based strategies in research and therapeutics relies on expanding the repertoire of chemical modifications to overcome persistent challenges, such as improving cellular uptake and delivery. Addressing...
2.
Berner A, Nath Das R, Bhuma N, Golebiewska J, Abrahamsson A, Andreasson M, et al.
J Am Chem Soc
. 2024 Mar;
146(10):6926-6935.
PMID: 38430200
G-quadruplex (G4) DNA structures are prevalent secondary DNA structures implicated in fundamental cellular functions, such as replication and transcription. Furthermore, G4 structures are directly correlated to human diseases such as...
3.
Andreasson M, Donzel M, Abrahamsson A, Berner A, Doimo M, Quiroga A, et al.
J Med Chem
. 2024 Jan;
67(3):2202-2219.
PMID: 38241609
G-Quadruplex (G4) DNA structures are important regulatory elements in central biological processes. Small molecules that selectively bind and stabilize G4 structures have therapeutic potential, and there are currently >1000 known...
4.
Kim H, Lim T, Ha G, Lee J, Kim J, Chang N, et al.
Exp Mol Med
. 2023 Aug;
55(9):2039-2050.
PMID: 37653040
Thus far, attempts to develop drugs that target corticotropin-releasing hormone receptor 1 (CRFR), a drug target in stress-related therapy, have been unsuccessful. Studies have focused on using high-resolution G protein-coupled...
5.
Doimo M, Chaudhari N, Abrahamsson S, LHote V, Nguyen T, Berner A, et al.
Nucleic Acids Res
. 2023 Jun;
51(14):7392-7408.
PMID: 37351621
Mitochondrial DNA (mtDNA) replication stalling is considered an initial step in the formation of mtDNA deletions that associate with genetic inherited disorders and aging. However, the molecular details of how...