Alphonse Charbel
Overview
Explore the profile of Alphonse Charbel including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
35
Followers
0
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Recent Articles
1.
Kommoss F, Charbel A, Kolin D, Howitt B, Kobel M, Lee J, et al.
Virchows Arch
. 2024 Oct;
485(5):793-803.
PMID: 39392508
Uterine mesenchymal tumours harboring KAT6B/A::KANSL1 gene fusions typically exhibit histological and immunophenotypic overlap with endometrial stromal and smooth muscle tumours. To date it remains uncertain whether such neoplasms should be...
2.
Grimsrud M, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, et al.
Hepatol Commun
. 2024 Jul;
8(7).
PMID: 38967597
Background: People with primary sclerosing cholangitis (PSC) have a 20% lifetime risk of biliary tract cancer (BTC). Using whole-exome sequencing, we characterized genomic alterations in tissue samples from BTC with...
3.
Albrecht T, Rossberg A, Rose F, Breuhahn K, Baumann E, Toth M, et al.
J Clin Pathol
. 2024 May;
PMID: 38749660
Aims: Intrahepatic cholangiocarcinoma (iCCA) is a diagnosis of exclusion that can pose a challenge to the pathologist despite thorough clinical workup. Although several immunohistochemical markers have been proposed for iCCA,...
4.
Albrecht T, Rossberg A, Albrecht J, Nicolay J, Straub B, Gerber T, et al.
Gastroenterology
. 2023 Aug;
165(5):1262-1275.
PMID: 37562657
Background & Aims: Diagnosis of adenocarcinoma in the liver is a frequent scenario in routine pathology and has a critical impact on clinical decision making. However, rendering a correct diagnosis...
5.
Charbel A, Tavernar L, Albrecht T, Brinkmann F, Verheij J, Roos E, et al.
Br J Cancer
. 2022 Sep;
127(9):1603-1614.
PMID: 36068277
Background: Intraductal papillary neoplasms (IPN) and biliary epithelial neoplasia (BilIN) are well-defined precursor lesions of biliary tract carcinoma (BTC). The aim of this study was to provide a comprehensive characterisation...
6.
Ploeger C, Schreck J, Huth T, Fraas A, Albrecht T, Charbel A, et al.
Cancers (Basel)
. 2022 Mar;
14(5).
PMID: 35267462
Liver cancers, which are mostly hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), are very aggressive tumors with poor prognosis. Therapeutic options with curative intent are largely limited to surgery and available...
7.
Albrecht T, Goeppert B, Brinkmann F, Charbel A, Zhang Q, Schreck J, et al.
Cancers (Basel)
. 2021 Dec;
13(24).
PMID: 34944891
Cholangiocarcinoma (CCA) is a heterogeneous malignancy with a dismal prognosis. Therapeutic options are largely limited to surgery and conventional chemotherapy offers limited benefit. As immunotherapy has proven highly effective in...
8.
Albrecht T, Brinkmann F, Albrecht M, Lonsdorf A, Mehrabi A, Hoffmann K, et al.
Cancers (Basel)
. 2021 Apr;
13(7).
PMID: 33918309
Inhibition of the programmed cell death protein-1/ligand-1 (PD-1/PD-L1) axis has opened a new era in the treatment of solid cancers. However, there is no data on the expression and relevance...