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Alok Bhushan

Explore the profile of Alok Bhushan including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 554
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Recent Articles
1.
Desai V, Tadinada S, Shaghaghi H, Summer R, Lai J, Bhushan A
Anticancer Res . 2024 May; 44(6):2307-2323. PMID: 38821627
Background/aim: Pancreatic cancer is an aggressive type of cancer, with a dismally low survival rate of <5%. FDA-approved drugs like gemcitabine have shown little therapeutic success, prolonging survival by a...
2.
Hokello J, Tyagi K, Owor R, Sharma A, Bhushan A, Daniel R, et al.
Life (Basel) . 2024 Jan; 14(1). PMID: 38255719
The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1) and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a result...
3.
Hokello J, Sharma A, Tyagi P, Bhushan A, Tyagi M
Vaccines (Basel) . 2021 Nov; 9(11). PMID: 34835203
The central nervous system (CNS) is highly compartmentalized and serves as a specific site of human immunodeficiency virus (HIV) infection. Therefore, an understanding of the cellular populations that are infected...
4.
Sharma N, Bhushan A, He J, Kaushal G, Bhardwaj V
Cancer Metab . 2020 Sep; 8:19. PMID: 32974013
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant forms of cancer. Lack of effective treatment options and drug resistance contributes to the low survival among PDAC patients. In...
5.
Mizue Terai , Londin E, Rochani A, Link E, Lam B, Kaushal G, et al.
Cancers (Basel) . 2020 Feb; 12(2). PMID: 32050636
Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Metastatic uveal melanoma (MUM) is highly resistant to...
6.
He J, Liu W, Ge X, Wang G, Desai V, Wang S, et al.
Toxicol Appl Pharmacol . 2019 Jun; 378:114606. PMID: 31170415
Inorganic arsenic is an environmental carcinogen that poses a major global public health risk. A high percentage of drinking water from wells in the U.S. contains higher-than-normal levels of arsenic,...
7.
Summer R, Shaghaghi H, Schriner D, Roque W, Sales D, Cuevas-Mora K, et al.
Am J Physiol Lung Cell Mol Physiol . 2019 Mar; 316(6):L1049-L1060. PMID: 30892080
Cellular senescence is a biological process by which cells lose their capacity to proliferate yet remain metabolically active. Although originally considered a protective mechanism to limit the formation of cancer,...
8.
Desai V, Jain A, Shaghaghi H, Summer R, Lai J, Bhushan A
Anticancer Res . 2018 Dec; 39(1):57-66. PMID: 30591440
Background/aim: Several epidemiological studies have reported the chemopreventive potential of biochanin A, in cancer development and progression. We investigated the anticancer potential of combination of biochanin A and temozolomide against...
9.
Shin Y, Kokate R, Desai V, Bhushan A, Kaushal G
Drug Discov Ther . 2018 Jul; 12(3):142-153. PMID: 29998995
D-cycloserine (DCS), a partial agonist at N-methyl-D-aspartate (NMDA) receptors, is used as an enhancer of exposure therapy for anxiety disorders. The purpose of the present study was to investigate the...
10.
Desai V, Bhushan A
Biomed Res Int . 2018 Jan; 2017:9363040. PMID: 29359162
Glioblastoma multiforme (GBM) is the most frequent, primary malignant brain tumor prevalent in humans. GBM characteristically exhibits aggressive cell proliferation and rapid invasion of normal brain tissue resulting in poor...