Allen Y Chung
Overview
Explore the profile of Allen Y Chung including associated specialties, affiliations and a list of published articles.
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5
Citations
466
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Recent Articles
1.
Ozbilge H, LeVea C, Chung A, Li Q, Egilmez N
Oncoimmunology
. 2015 Jul;
4(4):e1002724.
PMID: 26137401
Oral administration of particulate IL-10 suppressed polyposis, ameliorated systemic pathology and extended lifespan in APC mice. Therapeutic effect was associated with selective activity of IL-10 on intestinal CD4+Foxp3+RORγt+IL-17+ pathogenic T-regulatory...
2.
Chung A, Li Q, Blair S, De Jesus M, Dennis K, LeVea C, et al.
Cancer Res
. 2014 Sep;
74(19):5377-85.
PMID: 25228656
Immune dysregulation drives the pathogenesis of chronic inflammatory, autoimmune, and dysplastic disorders. While often intended to address localized pathology, most immune modulatory therapies are administered systemically and carry inherent risk...
3.
Xu H, Zhu J, Smith S, Foldi J, Zhao B, Chung A, et al.
Nat Immunol
. 2012 May;
13(7):642-50.
PMID: 22610140
Emerging concepts suggest that the functional phenotype of macrophages is regulated by transcription factors that define alternative activation states. We found that RBP-J, the main nuclear transducer of signaling via...
4.
Foldi J, Chung A, Xu H, Zhu J, Outtz H, Kitajewski J, et al.
J Immunol
. 2010 Sep;
185(9):5023-31.
PMID: 20870935
Several signaling pathways, including the Notch pathway, can modulate TLR activation to achieve responses most appropriate for the environment. One mechanism of TLR-Notch cross-talk is TLR-induced expression of Notch ligands...
5.
Hu X, Chung A, Wu I, Foldi J, Chen J, Ji J, et al.
Immunity
. 2008 Nov;
29(5):691-703.
PMID: 18976936
Toll-like receptor (TLR) responses are regulated to avoid toxicity and achieve coordinated responses appropriate for the cell environment. We found that Notch and TLR pathways cooperated to activate canonical Notch...