Alla Khodorova
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Explore the profile of Alla Khodorova including associated specialties, affiliations and a list of published articles.
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18
Citations
505
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Recent Articles
1.
Moradi Tuchayi S, Wang Y, Khodorova A, Pence I, Stemmer-Rachamimov A, Evans C, et al.
Sci Rep
. 2022 Nov;
12(1):19891.
PMID: 36400878
Cryoneurolysis is an opioid-sparing therapy for long-lasting and reversible reduction of pain. We developed a nerve-selective method for cryoneurolysis by local injection of ice-slurry (- 5 to - 6 °C)...
2.
Moradi Tuchayi S, Wang Y, Khodorova A, Pence I, Evans C, Anderson R, et al.
J Invest Dermatol
. 2022 Aug;
143(1):134-141.e1.
PMID: 35985498
Cutaneous pain is a common symptom of skin disease, and available therapies are inadequate. We developed a neural selective and injectable method of cryoneurolysis with ice slurry, which leads to...
3.
Garibyan L, Moradi Tuchayi S, Wang Y, Khodorova A, Stemmer-Rachamimov A, Purschke M, et al.
Anesthesiology
. 2020 Jan;
133(1):185-194.
PMID: 31977524
Background: Postoperative pain caused by trauma to nerves and tissue around the surgical site is a major problem. Perioperative steps to reduce postoperative pain include local anesthetics and opioids, the...
4.
Khodorova A, Nicol G, Strichartz G
Neuroscience
. 2016 Nov;
340:384-397.
PMID: 27826102
The p75 neurotrophin receptor (p75) and its activation of the sphingomyelin signaling cascade are essential for mechanical hypersensitivity resulting from locally injected nerve growth factor (NGF). Here the roles of...
5.
Strichartz G, Khodorova A, Wang J, Chen Y, Huang C
Anesth Analg
. 2015 Jul;
121(4):1065-1077.
PMID: 26218866
Background: Contralateral hyperalgesia, occurring after unilateral injury, is usually explained by central sensitization in spinal cord and brain. We previously reported that injection of endothelin-1 (ET-1) into one rat hindpaw...
6.
Barr T, Hrnjic A, Khodorova A, Sprague J, Strichartz G
Pain
. 2014 Feb;
155(6):1091-1101.
PMID: 24569146
Endothelin (ET-1), an endogenous peptide with a prominent role in cutaneous pain, causes mechanical hypersensitivity in the rat hind paw, partly through mechanisms involving local release of algogenic molecules in...
7.
Barr T, Kam S, Khodorova A, Montmayeur J, Strichartz G
Pharmacol Res
. 2011 Mar;
63(6):532-40.
PMID: 21352917
No abstract available.
8.
Khodorova A, Strichartz G
Can J Physiol Pharmacol
. 2010 Jul;
88(6):668-75.
PMID: 20628433
A profound tachyphylaxis of the acute nocifensive flinching (pain) response to subcutaneous injection of endothelin-1 (ET-1) into the hind paw footpad is shown by the reduced response to a second...
9.
Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G
Open Pain J
. 2010 Jun;
2:30-40.
PMID: 20559459
Injection of endothelin-1 (ET-1) into the plantar rat hindpaw causes acute pain at high concentrations and tactile sensitization at low concentrations. The pro-nociceptive actions are driven through ET(A) receptors for...
10.
Khodorova A, Richter J, Vasko M, Strichartz G
J Pain
. 2009 Jun;
10(7):740-9.
PMID: 19559390
Unlabelled: Intraplantar injection of endothelin-1 (ET-1) (1.5-10 muM) in the rat produces mechanical allodynia. Here we identify the receptor subtypes for ET-1, glutamate and CGRP critical to such allodynia. Antagonism...