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Alissa Nichles

Explore the profile of Alissa Nichles including associated specialties, affiliations and a list of published articles. Areas
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Citations 227
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Recent Articles
1.
Hickie I, Iorfino F, Rohleder C, Song Y, Nichles A, Zmicerevska N, et al.
BMJ Open . 2023 Oct; 13(10):e072082. PMID: 37821139
Objectives: Many adolescents and young adults with emerging mood disorders do not achieve substantial improvements in education, employment, or social function after receiving standard youth mental health care. We have...
2.
Amminger G, Rice S, Davey C, Quinn A, Hermens D, Zmicerevska N, et al.
Biol Psychiatry . 2023 Jun; 95(5):426-433. PMID: 37355004
Background: Clinical trials suggest that long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) (fish oil) may reduce depressive symptoms in adults with major depressive disorder. Therefore, n-3 PUFAs may be a...
3.
McHugh C, Ho N, Iorfino F, Crouse J, Nichles A, Zmicerevska N, et al.
Soc Psychiatry Psychiatr Epidemiol . 2023 Feb; 58(6):893-905. PMID: 36854811
Purpose: Machine learning (ML) has shown promise in modelling future self-harm but is yet to be applied to key questions facing clinical services. In a cohort of young people accessing...
4.
Wilson C, Carpenter J, Nichles A, Zmicerevska N, Song Y, McHugh C, et al.
BMJ Open . 2023 Feb; 13(2):e064682. PMID: 36810174
Introduction: Metformin is a medication likely to improve measures of cardiometabolic disturbance in young people with mental illness. Evidence also suggests metformin may improve depressive symptoms. This 52-week double-blind randomised...
5.
Carpenter J, Zmicerevska N, Crouse J, Nichles A, Garland A, Song Y, et al.
BMJ Open . 2023 Jan; 12(9):e056298. PMID: 36691133
Introduction: Sleep-wake and circadian disturbance is a key feature of mood disorders with a potential causal role and particular relevance to young people. Brexpiprazole is a second-generation antipsychotic medication with...
6.
Capon W, Hickie I, Varidel M, Prodan A, Crouse J, Carpenter J, et al.
BMC Med . 2022 Dec; 20(1):479. PMID: 36514113
Background: Clinical staging proposes that youth-onset mental disorders develop progressively, and that active treatment of earlier stages should prevent progression to more severe disorders. This retrospective cohort study examined the...
7.
McHugh C, Song Y, Zmicerevska N, Crouse J, Nichles A, Wilson C, et al.
BMJ Open . 2022 Feb; 12(2):e054264. PMID: 35190432
Introduction: Understanding the risk of premature death from suicide, accident and injury and other physical health conditions in people seeking healthcare for mental disorders is essential for delivering targeted clinical...
8.
Iorfino F, Carpenter J, Cross S, Crouse J, Davenport T, Hermens D, et al.
Med J Aust . 2021 Oct; 216(2):87-93. PMID: 34664282
Objective: To identify trajectories of social and occupational functioning in young people during the two years after presenting for early intervention mental health care; to identify demographic and clinical factors...
9.
Wilson C, Nichles A, Zmicerevska N, Carpenter J, Song Y, McHugh C, et al.
BMJ Open . 2021 Jun; 11(6):e044977. PMID: 34187819
Introduction: Worsened cardiometabolic profiles in youth with mental ill health have been associated with a number of modifiable lifestyle risk factors. It is becoming increasingly evident that clinical interventions need...
10.
Nichles A, Zmicerevska N, Song Y, Wilson C, McHugh C, Hamilton B, et al.
BMJ Open . 2021 Jun; 11(6):e044731. PMID: 34145010
Introduction: Approximately 75% of major mental illness occurs before the age of 25 years. Despite this, our capacity to provide effective, early and personalised interventions is limited by insufficient evidence...