Alison L Ruhe
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Explore the profile of Alison L Ruhe including associated specialties, affiliations and a list of published articles.
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8
Citations
294
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Recent Articles
1.
Kawakami T, Raghavan V, Ruhe A, Jensen M, Milano A, Nelson T, et al.
PLoS One
. 2022 Apr;
17(4):e0264365.
PMID: 35385474
Domestic dogs exhibit diverse types of both congenital and non-congenital hearing losses. Rhodesian Ridgebacks can suffer from a progressive hearing loss in the early stage of their life, a condition...
2.
Webb A, Ruhe A, Neff M
Can J Vet Res
. 2019 May;
83(2):142-148.
PMID: 31097876
Bilateral deafness with concurrent vestibular dysfunction was first reported in the Doberman pinscher in 1980. Here, we identify a coding mutation in the MYO7A gene that is perfectly associated with...
3.
Neff M, Beck J, Koeman J, Boguslawski E, Kefene L, Borgman A, et al.
PLoS One
. 2013 Jan;
7(12):e51917.
PMID: 23300579
A crippling dwarfism was first described in the Miniature Poodle in Great Britain in 1956. Here, we resolve the genetic basis of this recessively inherited disorder. A case-control analysis (8:8)...
4.
Wong A, Ruhe A, Biswas S, Robertson K, Ali A, Akey J, et al.
Anim Biotechnol
. 2012 Nov;
23(4):241-52.
PMID: 23134304
Short tandem repeat polymorphisms (STRPs) are robust and informative markers for a range of genetic applications. STRPs are advantageous in experimental designs that derive power from sampling many individuals rather...
5.
Yokoyama J, Lam E, Ruhe A, Erdman C, Robertson K, Webb A, et al.
PLoS Genet
. 2012 Oct;
8(9):e1002898.
PMID: 23028339
Domestic dogs can suffer from hearing losses that can have profound impacts on working ability and quality of life. We have identified a type of adult-onset hearing loss in Border...
6.
Bader H, Ruhe A, Wang L, Wong A, Walsh K, Packer R, et al.
PLoS One
. 2010 Sep;
5(9).
PMID: 20862248
Background: Musladin-Lueke Syndrome (MLS) is a hereditary disorder affecting Beagle dogs that manifests with extensive fibrosis of the skin and joints. In this respect, it resembles human stiff skin syndrome...
7.
Akey J, Ruhe A, Akey D, Wong A, Connelly C, Madeoy J, et al.
Proc Natl Acad Sci U S A
. 2010 Jan;
107(3):1160-5.
PMID: 20080661
The size, shape, and behavior of the modern domesticated dog has been sculpted by artificial selection for at least 14,000 years. The genetic substrates of selective breeding, however, remain largely...
8.
Wong A, Ruhe A, Dumont B, Robertson K, Guerrero G, Shull S, et al.
Genetics
. 2009 Dec;
184(2):595-605.
PMID: 19966068
We have leveraged the reference sequence of a boxer to construct the first complete linkage map for the domestic dog. The new map improves access to the dog's unique biology,...