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Alison C Roxby

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Recent Articles
1.
Theodore D, Neradilek M, Gillespie K, Edupuganti S, Hinojosa J, Lama J, et al.
J Acquir Immune Defic Syndr . 2025 Feb; 98(4):340-345. PMID: 39970314
Background: Realizing the potential of HIV prevention options requires understanding product tolerability across diverse groups vulnerable to HIV acquisition. Gender minority (GM) individuals are understudied in clinical trials. Setting: HVTN...
2.
Chawana T, Walsh S, Stranix-Chibanda L, Chirenje Z, Yu C, Zhang L, et al.
BMC Immunol . 2025 Feb; 26(1):8. PMID: 39966732
VRC07-523LS is a safe and well-tolerated monoclonal antibody (mAb) targeting the CD4 binding site on the HIV envelope (Env) trimer. Efficacy of VRC07-523LS, in combination with mAbs targeting other HIV...
3.
Naicker V, Laher F, Bekker L, Seaton K, Allen M, De Rosa S, et al.
PLOS Glob Public Health . 2024 Sep; 4(9):e0003319. PMID: 39302924
Induction of broad, durable immune responses is a challenge in HIV vaccine development. HVTN 100 Part A administered subtype C-containing ALVAC-HIV at months 0 and 1, and ALVAC-HIV with bivalent...
4.
Cantos V, Neradilek M, Huang Y, Roxby A, Gillespie K, deCamp A, et al.
Open Forum Infect Dis . 2024 Jul; 11(7):ofae387. PMID: 39035572
Background: HIV Vaccine Trials Network (HVTN) 704/085, a placebo-controlled clinical trial assessing the efficacy of VRC01 broadly neutralizing antibody infusion for HIV prevention, offered oral preexposure prophylaxis (PrEP) as the...
5.
Chihana R, Kee J, Moodie Z, Huang Y, Janes H, Dadabhai S, et al.
Vaccine . 2024 May; 42(20):125991. PMID: 38772835
Background: Reactogenicity informs vaccine safety, and may influence vaccine uptake. We evaluated factors associated with reactogenicity in HVTN 702, a typical HIV vaccine efficacy trial with multiple doses and products....
6.
Hybiske K, Paktinat S, Newman K, Patton D, Khosropour C, Roxby A, et al.
Infect Immun . 2024 Mar; 92(4):e0050323. PMID: 38451079
Non-neutralizing functions of antibodies, including phagocytosis, may play a role in (CT) infection, but these functions have not been studied and assays are lacking. We utilized a flow-cytometry-based assay to...
7.
Kopp C, Sobhani N, Baker B, Tapia K, Jain R, Hitti J, et al.
Infect Dis Clin Pract (Baltim Md) . 2024 Jan; 31(6). PMID: 38213314
Women who are pregnant and living with HIV have traditionally been excluded from clinical trials regarding new pharmacotherapy. Immediate initiation of antiretroviral therapy (ART) is recommended for women who are...
8.
Kipkurui N, Owidi E, Ayieko J, Owuor G, Mugenya I, Agot K, et al.
PLOS Glob Public Health . 2023 Sep; 3(9):e0002418. PMID: 37747873
In Kenya, adolescents spend much of their formative years in boarding secondary schools, which presents a challenging environment for antiretroviral (ART) adherence support among adolescents living with HIV (ALHIV). We...
9.
Simmons W, Chan J, Budak J, Dhanireddy S, Green M, Jain R, et al.
Antimicrob Steward Healthc Epidemiol . 2023 Jul; 3(1):e108. PMID: 37502242
Bacterial superinfection and antibiotic prescribing in the setting of the current mpox outbreak are not well described in the literature. This retrospective observational study revealed low prevalence (11%) of outpatient...
10.
Daniel A, Casmir E, Oluoch L, Micheni M, Kiptinness C, Wald A, et al.
BMC Pregnancy Childbirth . 2023 Jul; 23(1):493. PMID: 37403049
Background: Adolescent girls and young women (AGYW) have a high incidence of unplanned pregnancies, especially in low-resource settings. AGYW assess the overlapping risks of pregnancy, contraception, and STIs as they...