Aline Zbinden
Overview
Explore the profile of Aline Zbinden including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
168
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Recent Articles
1.
Schlunder K, Cipriano M, Zbinden A, Fuchs S, Mayr T, Schenke-Layland K, et al.
Lab Chip
. 2024 Mar;
24(7):2080-2093.
PMID: 38441218
Pancreatic research is of major importance to advance mechanistic understanding and development of treatment options for diseases such as diabetes mellitus. We present a thermoplastic-based microphysiological system aiming to model...
2.
Urbanczyk M, Jeyagaran A, Zbinden A, Lu C, Marzi J, Kuhlburger L, et al.
Matrix Biol
. 2023 Jan;
115:160-183.
PMID: 36592738
Transplantation of islets of Langerhans is a promising alternative treatment strategy in severe cases of type 1 diabetes mellitus; however, the success rate is limited by the survival rate of...
3.
Jeyagaran A, Lu C, Zbinden A, Birkenfeld A, Brucker S, Layland S
Adv Drug Deliv Rev
. 2022 Aug;
189:114481.
PMID: 36002043
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D) relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as well as the mechanisms responsible...
4.
Urbanczyk M, Zbinden A, Schenke-Layland K
Adv Drug Deliv Rev
. 2022 May;
186:114323.
PMID: 35568103
Endothelial cells (ECs) are a key cellular component of the vascular system as they form the inner lining of the blood vessels. Recent findings highlight that ECs express extensive phenotypic...
5.
Zbinden A, Cante-Barrett K, Pike-Overzet K, Staal F
Cells
. 2022 Jan;
11(1).
PMID: 35011669
The intrinsic capacity of human hematopoietic stem cells (hHSCs) to reconstitute myeloid and lymphoid lineages combined with their self-renewal capacity hold enormous promises for gene therapy as a viable treatment...
6.
Zbinden A, Layland S, Urbanczyk M, Carvajal Berrio D, Marzi J, Zauner M, et al.
Adv Sci (Weinh)
. 2021 Mar;
8(4):2002500.
PMID: 33643791
Ischemia impacts multiple organ systems and is the major cause of morbidity and mortality in the developed world. Ischemia disrupts tissue homeostasis, driving cell death, and damages tissue structure integrity....
7.
Zbinden A, Carvajal Berrio D, Urbanczyk M, Layland S, Bosch M, Fliri S, et al.
J Biophotonics
. 2020 Oct;
13(12):e202000375.
PMID: 33026180
Pancreatic islet isolation from donor pancreases is an essential step for the transplantation of insulin-secreting β-cells as a therapy to treat type 1 diabetes mellitus. This process however damages islet...
8.
Zbinden A, Urbanczyk M, Layland S, Becker L, Marzi J, Bosch M, et al.
Tissue Eng Part A
. 2020 Oct;
27(13-14):977-991.
PMID: 33023407
The use of biomaterials and biomaterial functionalization is a promising approach to support pancreatic islet viability posttransplantation in an effort to reduce insulin dependence for patients afflicted with diabetes mellitus...
9.
Urbanczyk M, Zbinden A, Layland S, Duffy G, Schenke-Layland K
Tissue Eng Part A
. 2019 Nov;
26(7-8):387-399.
PMID: 31680653
β-Cell functionality and survival are highly dependent on the cells' microenvironment and cell-cell interactions. Since the pancreas is a highly vascularized organ, the crosstalk between β-cells and endothelial cells (ECs)...
10.
Zbinden A, Marzi J, Schlunder K, Probst C, Urbanczyk M, Black S, et al.
Matrix Biol
. 2019 Jun;
85-86:205-220.
PMID: 31238092
The increasing prevalence of diabetes, its heterogeneity, and the limited number of treatment options drive the need for physiologically relevant assay platforms with human genetic background that have the potential...