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Alicia Barcena

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Articles 18
Citations 263
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Recent Articles
1.
Togarrati P, Dinglasan N, Yee E, Heitman J, Jackman R, Geisberg M, et al.
Transplant Direct . 2019 Jul; 5(6):e460. PMID: 31321294
Background: Membranes surrounding the fetus play a crucial role in providing a physical and immunological barrier between a semiallogeneic fetus and mother during pregnancy. In this study, we tested whether...
2.
Muench M, Kapidzic M, Gormley M, Gutierrez A, Ponder K, Fomin M, et al.
Development . 2017 Mar; 144(8):1399-1411. PMID: 28255007
We examined the contribution of the fetal membranes, amnion and chorion, to human embryonic and fetal hematopoiesis. A population of cells displaying a hematopoietic progenitor phenotype (CD34 CD45) of fetal...
3.
Ponder K, Barcena A, Bos F, Gormley M, Zhou Y, Ona K, et al.
Reprod Sci . 2016 Mar; 23(9):1179-92. PMID: 26944948
Background: The human placenta is a source of hematopoietic stem and progenitor cells (HSPCs). The RUNX1 transcription factor is required for the formation of functional HSPCs. The impact of preeclampsia...
4.
Barcena A
Lancet . 2014 Dec; 385(9975):e29-30. PMID: 25458717
No abstract available.
5.
Wang J, Huang V, Ye L, Barcena A, Lin G, Lue T, et al.
Stem Cells Dev . 2014 Sep; 24(3):345-53. PMID: 25232932
Ectopic overexpression of transcription factors has been used to reprogram cell fate. For example, virus-mediated overexpression of four transcription factors OCT4, SOX2, MYC, and KLF4, known as Yamanaka factors, can...
6.
Muench M, Beyer A, Fomin M, Thakker R, Mulvaney U, Nakamura M, et al.
PLoS One . 2014 May; 9(5):e97312. PMID: 24819392
The liver plays a vital role in hematopoiesis during mammalian prenatal development but its hematopoietic output declines during the perinatal period. Nonetheless, hepatic hematopoiesis is believed to persist into adulthood....
7.
Co E, Gormley M, Kapidzic M, Rosen D, Scott M, Stolp H, et al.
Biol Reprod . 2013 Apr; 88(6):155. PMID: 23553431
Human pregnancy is an immunological paradox. Semiallogeneic (fetal) placental cells (extravillous cytotrophoblasts [CTBs]) invade the uterine lining (decidua), which contains a unique decidual natural killer (dNK) cell population, identified by...
8.
Barcena A, Muench M, Kapidzic M, Gormley M, Goldfien G, Fisher S
Transfusion . 2011 Nov; 51 Suppl 4:94S-105S. PMID: 22074633
Background: Hematopoietic stem cell (HSC) transplantation is an essential element of medical therapy, leading to cures of previously incurable hematological and nonhematological diseases. Many patients do not find matched donors...
9.
Varga N, Barcena A, Fomin M, Muench M
Stem Cell Stud . 2011 May; 1(1). PMID: 21603093
Immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl)/SzJ (NSG) mice are a valuable resource to study human hematopoietic stem cells. Prolonged multilineage hematopoiesis indicates stem cell engraftment and generally is measured by flow cytometry. In...
10.
Fomin M, Tai L, Barcena A, Muench M
Stem Cells Dev . 2010 Oct; 20(7):1247-57. PMID: 20964518
The molecular and cellular profile of liver cells during early human development is incomplete, complicating the isolation and study of hepatocytes, cholangiocytes, and hepatic stem cells from the complex amalgam...