Alice Wey
Overview
Explore the profile of Alice Wey including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
193
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Recent Articles
1.
Martinez-Cerdeno V, Lemen J, Chan V, Wey A, Lin W, Dent S, et al.
PLoS One
. 2012 Jun;
7(6):e39456.
PMID: 22745758
Here we examine the functions of the Myc cofactor and histone acetyltransferase, GCN5/KAT2A, in neural stem and precursor cells (NSC) using a conditional knockout approach driven by nestin-cre. Mice with...
2.
Wey A, Martinez Cerdeno V, Pleasure D, Knoepfler P
Cerebellum
. 2010 Jul;
9(4):537-47.
PMID: 20658325
Separate murine knockout (KO) of either c- or N-myc genes in neural stem and precursor cells (NSC) driven by nestin-cre causes microcephaly. The cerebellum is particularly affected in the N-myc...
3.
Wey A, Knoepfler P
Oncotarget
. 2010 Jul;
1(2):120-30.
PMID: 20651942
myc genes are associated with a wide variety of human cancers including most types of nervous system tumors. While the mechanisms by which myc overexpression causes tumorigenesis are multifaceted and...
4.
Cotterman R, Jin V, Krig S, Lemen J, Wey A, Farnham P, et al.
Cancer Res
. 2008 Dec;
68(23):9654-62.
PMID: 19047142
Myc proteins have long been modeled to operate strictly as classic gene-specific transcription factors; however, we find that N-Myc has a robust role in the human genome in regulating global...
5.
Martins R, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, et al.
Genes Dev
. 2008 Jan;
22(2):179-93.
PMID: 18198336
Myc family members play crucial roles in regulating cell proliferation, size, differentiation, and survival during development. We found that N-myc is expressed in retinal progenitor cells, where it regulates proliferation...