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Alice Baynes

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Articles 13
Citations 39
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Recent Articles
1.
Imiuwa M, Baynes A, Kanda R, Routledge E
Ecotoxicol Environ Saf . 2024 Jun; 281:116656. PMID: 38945099
Antidepressant drugs (ADDs) are one of the most extensively used pharmaceuticals globally. They act at particularly low therapeutic concentrations to modulate monoamine neurotransmission, which is one of the most evolutionary...
2.
Baynes A, Lange A, Beresford N, Bryden E, Whitlock K, Tyler C, et al.
Environ Sci Technol . 2023 Aug; 57(34):12632-12641. PMID: 37595157
Endocrine disruption of wild fish, primarily resulting in the feminization of males, has been reported in English river sites for several decades. Estrogenic activity emanating from wastewater treatment works (WwTW)...
3.
Imiuwa M, Baynes A, Routledge E
PLoS One . 2023 Jun; 18(6):e0287582. PMID: 37368915
Background: The environmental prevalence of widely prescribed human pharmaceuticals that target key evolutionary conserved biomolecules present across phyla is concerning. Antidepressants, one of the most widely consumed pharmaceuticals globally, have...
4.
Hamilton P, Baynes A, Nicol E, Harris G, Uren Webster T, Beresford N, et al.
Aquat Toxicol . 2022 Jun; 249:106229. PMID: 35753216
Experimental exposures aimed at assessing the risks posed by estrogens in waste-water treatment work (WwTW) effluents to fish populations have rarely considered whether populations differ in their sensitivity to estrogenic...
5.
Wang Y, Baynes A, Renner K, Zhang M, Scrimshaw M, Routledge E
Toxics . 2022 Feb; 10(2). PMID: 35202273
The presence of plastic cosmetic microbeads in the environment due to their extensive use in society and inevitable dispersal into wastewater is concerning. Therefore, it is vital to understand the...
6.
Hamilton P, Lockyer A, Uren Webster T, Studholme D, Paris J, Baynes A, et al.
Environ Sci Technol . 2020 Nov; 54(24):15935-15945. PMID: 33227200
Exposure of male fish to estrogenic substances from wastewater treatment works (WwTWs) results in feminization and reduced reproductive fitness. Nevertheless, self-sustaining populations of roach () inhabit river stretches polluted with...
7.
Baynes A, Montagut Pino G, Duong G, Lockyer A, McDougall C, Jobling S, et al.
Sci Rep . 2019 Nov; 9(1):16439. PMID: 31712739
In vertebrates, the steroidogenesis enzyme 5α-reductase converts testosterone to the more potent androgen 5α-dihydrotestosterone. Homologues of 5α-reductase genes have been identified in molluscs. However, recent findings suggest that vertebrate-type steroid...
8.
Beresford N, Baynes A, Kanda R, Mills M, Arias-Salazar K, Collins T, et al.
J Vis Exp . 2016 Sep; (115). PMID: 27684328
Endocrine Disrupting Compounds pose a substantial risk to the aquatic environment. Ethinylestradiol (EE2) and estrone (E1) have recently been included in a watch list of environmental pollutants under the European...
9.
Kaur S, Baynes A, Lockyer A, Routledge E, Jones C, Noble L, et al.
PLoS One . 2016 Jul; 11(7):e0159852. PMID: 27448327
Gastropod mollusks have been proposed as alternative models for male reproductive toxicity testing, due to similarities in their reproductive anatomy compared to mammals, together with evidence that endocrine disrupting chemicals...
10.
Mills M, Arias-Salazar K, Baynes A, Shen L, Churchley J, Beresford N, et al.
Sci Rep . 2015 Jun; 5:10511. PMID: 26068117
17α-ethinylestradiol (EE2), a synthetic oestrogen in oral contraceptives, is one of many pharmaceuticals found in inland waterways worldwide as a result of human consumption and excretion into wastewater treatment systems....