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Alia Fleury

Explore the profile of Alia Fleury including associated specialties, affiliations and a list of published articles. Areas
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Citations 112
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Recent Articles
1.
Capello M, Fahrmann J, Rios Perez M, Vykoukal J, Irajizad E, Tripathi S, et al.
JCO Precis Oncol . 2022 Jan; 4:426-436. PMID: 35050739
Purpose: The combination chemotherapy of fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) has provided clinically meaningful improvement for pancreatic ductal adenocarcinoma (PDAC). We previously uncovered a role for the serine hydrolase...
2.
Chen Y, Capello M, Rios Perez M, Vykoukal J, Roife D, Kang Y, et al.
Mol Metab . 2021 Dec; 56:101426. PMID: 34971802
Objective: Intra-tumoral expression of the serine hydrolase carboxylesterase 2 (CES2) contributes to the activation of the pro-drug irinotecan in pancreatic ductal adenocarcinoma (PDAC). Given other potential roles of CES2, we...
3.
Vykoukal J, Fahrmann J, Gregg J, Tang Z, Basourakos S, Irajizad E, et al.
Nat Commun . 2020 Aug; 11(1):4279. PMID: 32855410
Plasma and tumor caveolin-1 (Cav-1) are linked with disease progression in prostate cancer. Here we report that metabolomic profiling of longitudinal plasmas from a prospective cohort of 491 active surveillance...
4.
Burks J, Fleury A, Livingston S, Smith J
Cancer Immunol Immunother . 2019 Nov; 68(12):2029-2039. PMID: 31709456
Interferon-stimulated gene 15 (ISG15) is a 15 kDa protein induced by type I interferons (IFN-α and IFN-β) and is a member of the ubiquitin-like superfamily of proteins. The ISG15 pathway...
5.
Fahrmann J, Vykoukal J, Fleury A, Tripathi S, Dennison J, Murage E, et al.
J Natl Cancer Inst . 2019 Sep; 112(6):607-616. PMID: 31503278
Background: MYC is an oncogenic driver of development and progression in triple-negative breast cancer (TNBC). Ornithine decarboxylase, the rate-limiting enzyme in polyamine metabolism, is a transcriptional target of MYC. We...