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Algera Goga

Explore the profile of Algera Goga including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 134
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Recent Articles
1.
Marcinkevics R, Silva P, Hankele A, Dornte C, Kadelka S, Csik K, et al.
Front Immunol . 2023 Jun; 14:1158905. PMID: 37313411
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces B and T cell responses, contributing to virus neutralization. In a cohort of 2,911 young adults, we identified 65 individuals who...
2.
Goga A, Stoffel M
Nat Rev Drug Discov . 2022 Feb; 21(6):417-439. PMID: 35210608
Recent years have seen unprecedented activity in the development of RNA-silencing oligonucleotide therapeutics for metabolic diseases. Improved oligonucleotide design and optimization of synthetic nucleic acid chemistry, in combination with the...
3.
Ge W, Goga A, He Y, Silva P, Hirt C, Herrmanns K, et al.
Gastroenterology . 2021 Sep; 162(1):269-284. PMID: 34547282
Background & Aims: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor that is almost uniformly lethal in humans. Activating mutations of KRAS are found in >90% of human PDACs...
4.
Goga A, Yagabasan B, Herrmanns K, Godbersen S, Silva P, Denzler R, et al.
Nat Commun . 2021 Jun; 12(1):3339. PMID: 34099655
The intestinal epithelium is a complex structure that integrates digestive, immunological, neuroendocrine, and regenerative functions. Epithelial homeostasis is maintained by a coordinated cross-talk of different epithelial cell types. Loss of...
5.
Lampert F, Stafa D, Goga A, Soste M, Gilberto S, Olieric N, et al.
Elife . 2018 Jun; 7. PMID: 29911972
In yeast, the glucose-induced degradation-deficient (GID) E3 ligase selectively degrades superfluous gluconeogenic enzymes. Here, we identified all subunits of the mammalian GID/CTLH complex and provide a comprehensive map of its...
6.
Ioris R, Galie M, Ramadori G, Anderson J, Charollais A, Konstantinidou G, et al.
Cell Rep . 2017 Feb; 18(8):1858-1868. PMID: 28228253
Cancer stem cells (CSCs) have high tumorigenic capacity. Here, we show that stem-like traits of specific human cancer cells are reduced by overexpression of the histone deacetylase sirtuin 6 (SIRT6)....