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Alfred Pozarickij

Explore the profile of Alfred Pozarickij including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 109
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Recent Articles
1.
Wang B, Pozarickij A, Mazidi M, Wright N, Yao P, Said S, et al.
Nat Commun . 2025 Feb; 16(1):1869. PMID: 39984443
Proteomics offers unique insights into human biology and drug development, but few studies have directly compared the utility of different proteomics platforms. We measured plasma levels of 2168 proteins in...
2.
Mazidi M, Wright N, Yao P, Kartsonaki C, Millwood I, Fry H, et al.
Eur J Epidemiol . 2024 Nov; 39(11):1229-1240. PMID: 39578299
Plasma proteomics could enhance risk prediction for multiple diseases beyond conventional risk factors or polygenic scores (PS). To assess utility of proteomics for risk prediction of ischemic heart disease (IHD)...
3.
Iona A, Yao P, Pozarickij A, Kartsonaki C, Said S, Wright N, et al.
Commun Biol . 2024 Oct; 7(1):1327. PMID: 39406990
Adiposity is an established risk factor for multiple diseases, but the causal relationships of different adiposity types with circulating protein biomarkers have not been systematically investigated. We examine the causal...
4.
Pozarickij A, Gan W, Lin K, Clarke R, Fairhurst-Hunter Z, Koido M, et al.
Nat Commun . 2024 Jul; 15(1):6265. PMID: 39048560
Elevated blood pressure (BP) is major risk factor for cardiovascular diseases (CVD). Genome-wide association studies (GWAS) conducted predominantly in populations of European ancestry have identified >2,000 BP-associated loci, but other...
5.
Kentistou K, Kaisinger L, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, et al.
Nat Genet . 2024 Jul; 56(8):1763-1764. PMID: 38982295
No abstract available.
6.
Kentistou K, Kaisinger L, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, et al.
Nat Genet . 2024 Jul; 56(7):1397-1411. PMID: 38951643
Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying 1,080 signals for age at menarche. Collectively, these explained 11%...
7.
Yao P, Iona A, Pozarickij A, Said S, Wright N, Lin K, et al.
Diabetes Care . 2024 Apr; 47(6):1012-1019. PMID: 38623619
Objective: Integrated analyses of plasma proteomics and genetic data in prospective studies can help assess the causal relevance of proteins, improve risk prediction, and discover novel protein drug targets for...
8.
Mazidi M, Wright N, Yao P, Kartsonaki C, Millwood I, Fry H, et al.
J Am Coll Cardiol . 2023 Nov; 82(20):1906-1920. PMID: 37940228
Background: Integrated analyses of plasma proteomic and genetic markers in prospective studies can clarify the causal relevance of proteins and discover novel targets for ischemic heart disease (IHD) and other...
9.
Shrine N, Izquierdo A, Chen J, Packer R, Hall R, Guyatt A, et al.
Nat Genet . 2023 Sep; 55(10):1778-1779. PMID: 37749248
No abstract available.
10.
Yao P, Iona A, Kartsonaki C, Said S, Wright N, Lin K, et al.
Eur J Epidemiol . 2023 Sep; 38(10):1089-1103. PMID: 37676424
Adiposity is associated with multiple diseases and traits, but little is known about the causal relevance and mechanisms underlying these associations. Large-scale proteomic profiling, especially when integrated with genetic data,...