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Alfonso Rubio-Navarro

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Articles 41
Citations 906
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Recent Articles
1.
Homan E, Gilani A, Rubio-Navarro A, Johnson M, Schaepkens O, Cortada E, et al.
Elife . 2025 Jan; 13. PMID: 39773465
Together with obesity and type 2 diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global epidemic. Activation of the complement system and infiltration of macrophages has been linked...
2.
Cortada E, Yao J, Xia Y, Dundar F, Zumbo P, Yang B, et al.
Commun Biol . 2024 Dec; 7(1):1611. PMID: 39627536
The immune system coordinates the response to cardiac injury and controls regenerative and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation associated with heart failure. Adult mice...
3.
Matsui M, Lynch L, Distefano I, Galante A, Gade A, Wang H, et al.
Nat Commun . 2024 Oct; 15(1):8980. PMID: 39420001
The canonical G406R mutation that increases Ca influx through the CACNA1C-encoded Ca1.2 Ca channel underlies the multisystem disorder Timothy syndrome (TS), characterized by life-threatening arrhythmias. Severe episodic hypoglycemia is among...
4.
Homan E, Gilani A, Rubio-Navarro A, Johnson M, Schaepkens O, Cortada E, et al.
medRxiv . 2024 Jul; PMID: 38978661
Together with obesity and type 2 diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global epidemic. Activation of the complement system and infiltration of macrophages has been linked...
5.
Ma L, Gilani A, Rubio-Navarro A, Cortada E, Li A, Reilly S, et al.
JCI Insight . 2024 May; 9(11). PMID: 38713526
Thermogenesis in beige/brown adipose tissues can be leveraged to combat metabolic disorders such as type 2 diabetes and obesity. The complement system plays pleiotropic roles in metabolic homeostasis and organismal...
6.
Guerrero-Hue M, Vallejo-Mudarra M, Garcia-Caballero C, Cordoba-David G, Palomino-Antolin A, Herencia C, et al.
Biomed Pharmacother . 2023 Nov; 169:115925. PMID: 38007933
Background: Rhabdomyolysis is a severe clinical syndrome associated to acute kidney injury (AKI) and chronic kidney disease (CKD). TWEAK/Fn14 signaling axis regulates renal inflammation and tubular cell death. However, the...
7.
Farooqui Z, Moreno J, Rubio-Navarro A
Front Pharmacol . 2023 May; 14:1193005. PMID: 37138849
No abstract available.
8.
Cortada E, Yao J, Xia Y, Dundar F, Zumbo P, Yang B, et al.
bioRxiv . 2023 Mar; PMID: 36993713
The immune system coordinates the response to cardiac injury and is known to control regenerative and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation associated with heart...
9.
Rubio-Navarro A, Gomez-Banoy N, Stoll L, Dundar F, Mawla A, Ma L, et al.
Nat Cell Biol . 2023 Mar; 25(4):565-578. PMID: 36928765
The pancreatic islets are composed of discrete hormone-producing cells that orchestrate systemic glucose homeostasis. Here we identify subsets of beta cells using a single-cell transcriptomic approach. One subset of beta...
10.
Mighty J, Rubio-Navarro A, Shi C, Zhou J, Flores-Bellver M, Heissel S, et al.
Front Endocrinol (Lausanne) . 2023 Jan; 13:1077644. PMID: 36686464
Introduction: Diabetic Retinopathy (DR) is a potentially blinding retinal disorder that develops through the pathogenesis of diabetes. The lack of disease predictors implies a poor prognosis with frequent irreversible retinal...