Alexey Kazantsev
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Explore the profile of Alexey Kazantsev including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
30
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Recent Articles
1.
Fokina V, Lobastova T, Tarlachkov S, Shutov A, Kazantsev A, Donova M
Curr Microbiol
. 2025 Feb;
82(4):143.
PMID: 39969609
Molecular mechanisms of C-steroid core degradation have been intensively studied mostly in mycolic acid rich actinobacteria, mainly in the representatives of Mycobacterium, Mycolicibacterium and Rhodococcus genera, whilst much less data...
2.
Karpov M, Strizhov N, Novikova L, Lobastova T, Khomutov S, Shutov A, et al.
Microb Cell Fact
. 2024 Apr;
23(1):105.
PMID: 38594656
Background: Pregnenolone and progesterone are the life-important steroid hormones regulating essential vital functions in mammals, and widely used in different fields of medicine. Microbiological production of these compounds from sterols...
3.
Kollerov V, Tarlachkov S, Shutov A, Kazantsev A, Donova M
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139084
The hydroxylation of steroids in the C7β position is one of the rare reactions that allow the production of value-added precursors in the synthesis of ursodeoxycholic acid and other pharmaceuticals....
4.
Lobastova T, Fokina V, Tarlachkov S, Shutov A, Bragin E, Kazantsev A, et al.
Microorganisms
. 2021 Dec;
9(12).
PMID: 34946155
The application of thermophilic microorganisms opens new prospects in steroid biotechnology, but little is known to date on steroid catabolism by thermophilic strains. The thermophilic strain VKM Ac-666 has been...
5.
Kollerov V, Shutov A, Kazantsev A, Donova M
Appl Microbiol Biotechnol
. 2021 Dec;
106(2):535-548.
PMID: 34939135
In this paper, we studied the transformation of two 3β-hydroxy-5-ene-steroids-pregnenolone and dehydroepiandrosterone (DHEA) by Backusella lamprospora VKM F- 944. The soil-dwelling zygomycete wild-type strain has been earlier selected during the...
6.
Kollerov V, Shutov A, Kazantsev A, Donova M
Fungal Biol
. 2021 Dec;
126(1):91-100.
PMID: 34930562
Fungal strain Drechslera sp. Ph F-34 was shown to modify 3-oxo- and 3-hydroxy steroids of androstane series to form the corresponding allylic 7-alcohols and 17β-reduced derivatives thus evidencing the presence...
7.
Kollerov V, Shutov A, Kazantsev A, Donova M
Phytochemistry
. 2019 Oct;
169:112160.
PMID: 31600654
Filamentous fungi is a huge phylum of lower eukaryotes with diverse activities towards various substrates, however, their biocatalytic potential towards steroids remains greatly underestimated. In this study, more than forty...
8.
Sukhodolskaya G, Fokina V, Shutov A, Nikolayeva V, Savinova T, Grishin Y, et al.
Steroids
. 2016 Nov;
118:9-16.
PMID: 27864019
The newly synthesized (α/β)-diastereomers of 6-(N-methyl-N-phenyl)aminomethylandrost-4-ene-3,17-dione (5) and 6-(N-methyl-N-phenyl)aminomethylandrost-4-en-17β-ol-3-one (6) were firstly investigated as substrates for the whole cells of Nocardioides simplex VKM Ac-2033D in comparison with their unsubstituted analogs,...
9.
Bunik V, Artiukhov A, Kazantsev A, Goncalves R, Daloso D, Oppermann H, et al.
Oncotarget
. 2015 Oct;
6(37):40036-52.
PMID: 26503465
The pyruvate dehydrogenase complex (PDHC) and its phosphorylation are considered essential for oncotransformation, but it is unclear whether cancer cells require PDHC to be functional or silenced. We used specific...