Alexei Tikhonov
Overview
Explore the profile of Alexei Tikhonov including associated specialties, affiliations and a list of published articles.
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30
Citations
1089
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Recent Articles
21.
Willerslev E, Davison J, Moora M, Zobel M, Coissac E, Edwards M, et al.
Nature
. 2014 Feb;
506(7486):47-51.
PMID: 24499916
Although it is generally agreed that the Arctic flora is among the youngest and least diverse on Earth, the processes that shaped it are poorly understood. Here we present 50...
22.
Guil-Guerrero J, Tikhonov A, Rodriguez-Garcia I, Protopopov A, Grigoriev S, Ramos-Bueno R
PLoS One
. 2014 Jan;
9(1):e84480.
PMID: 24416235
The elucidation of the sources of n-3 fatty acids available for the humans in the Upper Palaeolithic and Neolithic is highly relevant in order to ascertain the availability of such...
23.
Pedersen J, Valen E, Vargas Velazquez A, Parker B, Rasmussen M, Lindgreen S, et al.
Genome Res
. 2013 Dec;
24(3):454-66.
PMID: 24299735
Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next-generation sequence...
24.
Lorenzen E, Nogues-Bravo D, Orlando L, Weinstock J, Binladen J, Marske K, et al.
Nature
. 2011 Nov;
479(7373):359-64.
PMID: 22048313
Despite decades of research, the roles of climate and humans in driving the dramatic extinctions of large-bodied mammals during the Late Quaternary period remain contentious. Here we use ancient DNA,...
25.
Campos P, Kristensen T, Orlando L, Sher A, Kholodova M, Gotherstrom A, et al.
Mol Ecol
. 2010 Sep;
19(22):4863-75.
PMID: 20874761
Prior to the Holocene, the range of the saiga antelope (Saiga tatarica) spanned from France to the Northwest Territories of Canada. Although its distribution subsequently contracted to the steppes of...
26.
Campos P, Willerslev E, Sher A, Orlando L, Axelsson E, Tikhonov A, et al.
Proc Natl Acad Sci U S A
. 2010 Mar;
107(12):5675-80.
PMID: 20212118
The causes of the late Pleistocene megafaunal extinctions are poorly understood. Different lines of evidence point to climate change, the arrival of humans, or a combination of these events as...
27.
Miller W, Drautz D, Ratan A, Pusey B, Qi J, Lesk A, et al.
Nature
. 2008 Nov;
456(7220):387-90.
PMID: 19020620
In 1994, two independent groups extracted DNA from several Pleistocene epoch mammoths and noted differences among individual specimens. Subsequently, DNA sequences have been published for a number of extinct species....
28.
Intraspecific phylogenetic analysis of Siberian woolly mammoths using complete mitochondrial genomes
Gilbert M, Drautz D, Lesk A, Ho S, Qi J, Ratan A, et al.
Proc Natl Acad Sci U S A
. 2008 Jun;
105(24):8327-32.
PMID: 18541911
We report five new complete mitochondrial DNA (mtDNA) genomes of Siberian woolly mammoth (Mammuthus primigenius), sequenced with up to 73-fold coverage from DNA extracted from hair shaft material. Three of...
29.
Gilbert M, Tomsho L, Rendulic S, Packard M, Drautz D, Sher A, et al.
Science
. 2007 Sep;
317(5846):1927-30.
PMID: 17901335
Although the application of sequencing-by-synthesis techniques to DNA extracted from bones has revolutionized the study of ancient DNA, it has been plagued by large fractions of contaminating environmental DNA. The...
30.
Poinar H, Schwarz C, Qi J, Shapiro B, MacPhee R, Buigues B, et al.
Science
. 2005 Dec;
311(5759):392-4.
PMID: 16368896
We sequenced 28 million base pairs of DNA in a metagenomics approach, using a woolly mammoth (Mammuthus primigenius) sample from Siberia. As a result of exceptional sample preservation and the...