Alexandru Almasan
Overview
Explore the profile of Alexandru Almasan including associated specialties, affiliations and a list of published articles.
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64
Citations
8119
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Recent Articles
1.
Choudhary G, Tat T, Misra S, Hill B, Smith M, Almasan A, et al.
Oncotarget
. 2024 Jul;
15:468-469.
PMID: 39007277
No abstract available.
2.
Zhang Z, Samsa W, De Y, Zhang F, Reizes O, Almasan A, et al.
Nucleic Acids Res
. 2023 Feb;
51(5):2238-2256.
PMID: 36794849
The 53BP1-dependent end-joining pathway plays a critical role in double-strand break (DSB) repair. However, the regulators of 53BP1 in chromatin remain incompletely characterized. In this study, we identified HDGFRP3 (hepatoma-derived...
3.
Zhang F, Lou L, Peng B, Song X, Reizes O, Almasan A, et al.
Cancer Res
. 2022 Aug;
82(15):2807.
PMID: 35919993
No abstract available.
4.
Kapoor I, Bodo J, Hill B, Almasan A
Cell Death Dis
. 2021 Nov;
12(11):1061.
PMID: 34750354
Aberrant microRNA (miR) expression plays an important role in pathogenesis of different types of cancers, including B-cell lymphoid malignancies and in the development of chemo-sensitivity or -resistance in chronic lymphocytic...
5.
Fang X, Huang Z, Zhai K, Huang Q, Tao W, Kim L, et al.
Sci Transl Med
. 2021 Jul;
13(600).
PMID: 34193614
Glioblastoma (GBM), a lethal primary brain tumor, contains glioma stem cells (GSCs) that promote malignant progression and therapeutic resistance. SOX2 is a core transcription factor that maintains the properties of...
6.
Sharma A, Almasan A
Adv Cancer Res
. 2021 Apr;
150:249-284.
PMID: 33858598
The use of DNA-damaging agents such as radiotherapy and chemotherapy has been a mainstay treatment protocol for many cancers, including lung and prostate. Recently, FDA approval of inhibitors of DNA...
7.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
8.
Feng H, Lu J, Song X, Thongkum A, Zhang F, Lou L, et al.
Nucleic Acids Res
. 2021 Jan;
49(4):2400-2401.
PMID: 33511404
No abstract available.
9.
Kapoor I, Bodo J, Hill B, Hsi E, Almasan A
Cell Death Dis
. 2020 Nov;
11(11):941.
PMID: 33139702
Defects in apoptosis can promote tumorigenesis and impair responses of malignant B cells to chemotherapeutics. Members of the B-cell leukemia/lymphoma-2 (BCL-2) family of proteins are key regulators of the intrinsic,...
10.
Feng H, Lu J, Song X, Thongkum A, Zhang F, Lou L, et al.
Nucleic Acids Res
. 2020 Oct;
48(19):10940-10952.
PMID: 33010150
ATR functions as a master regulator of the DNA-damage response. ATR activation requires the ATR activator, topoisomerase IIβ-binding protein 1 (TopBP1). However, the underlying mechanism of TopBP1 regulation and how...