Alexandre Hiroaki Kihara
Overview
Explore the profile of Alexandre Hiroaki Kihara including associated specialties, affiliations and a list of published articles.
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45
Citations
470
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Recent Articles
1.
Zhou Z, Kihara A
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39518887
Neurodegenerative disorders are multiple chronic neurological diseases that pose a serious public health risk to our society, especially among the aging population [...].
2.
Kihara A
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39456975
Throughout development, gamma-aminobutyric acid, or GABA, plays a role in the proliferation, migration, and differentiation of neural progenitor cells [...].
3.
Bovi Dos Santos G, de Lima-Vasconcellos T, Movio M, Birbrair A, Del Debbio C, Kihara A
Stem Cell Rev Rep
. 2024 Feb;
20(3):722-737.
PMID: 38319527
Inherited and non-inherited retinopathies can affect distinct cell types, leading to progressive cell death and visual loss. In the last years, new approaches have indicated exciting opportunities to treat retinopathies....
4.
Movio M, Almeida G, Martines I, Barros de Lima G, Sasaki S, Kihara A, et al.
Viruses
. 2024 Jan;
16(1).
PMID: 38275971
Severe cases of SARS-CoV-2 infection are characterized by an immune response that leads to the overproduction of pro-inflammatory cytokines, resulting in lung damage, cardiovascular symptoms, hematologic symptoms, acute kidney injury...
5.
Zhou Z, Kihara A
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762040
Neurodegenerative diseases are characterized by the progressive degeneration or death of neurons in the central or peripheral nervous system [...].
6.
Fabres R, Cardoso D, Aragon B, Arruda B, Martins P, Ikebara J, et al.
Mol Cell Neurosci
. 2023 Jun;
126:103864.
PMID: 37268283
Oxygen deprivation is one of the main causes of morbidity and mortality in newborns, occurring with a higher prevalence in preterm infants, reaching 20 % to 50 % mortality in...
7.
Higa G, Francis-Oliveira J, Carlos-Lima E, Tamais A, Borges F, Kihara A, et al.
Sci Rep
. 2022 Dec;
12(1):21015.
PMID: 36470912
Important functions of the prefrontal cortex (PFC) are established during early life, when neurons exhibit enhanced synaptic plasticity and synaptogenesis. This developmental stage drives the organization of cortical connectivity, responsible...
8.
Movio M, de Lima-Vasconcellos T, Bovi Dos Santos G, Echeverry M, Colombo E, Mattos L, et al.
Semin Cell Dev Biol
. 2022 Oct;
144:77-86.
PMID: 36210260
Human-induced pluripotent stem cells (hiPSCs) have provided new methods to study neurodegenerative diseases. In addition to their wide application in neuronal disorders, hiPSCs technology can also encompass specific conditions, such...
9.
Marques B, Maciel G, Brito Junior M, Dias L, Scalzo S, Santos A, et al.
Semin Cell Dev Biol
. 2022 Oct;
144:11-19.
PMID: 36202693
The world population's life expectancy is growing, and neurodegenerative disorders common in old age require more efficient therapies. In this context, neural stem cells (NSCs) are imperative for the development...
10.
Santos A, Scalzo S, de Souza R, Santana P, Marques B, Oliveira L, et al.
Semin Cell Dev Biol
. 2022 Oct;
144:3-10.
PMID: 36192310
Organoid development and organ-on-a-chip are technologies based on differentiating stem cells, forming 3D multicellular structures resembling organs and tissues in vivo. Hence, both can be strategically used for disease modeling,...