» Authors » Alexandre D Baffet

Alexandre D Baffet

Explore the profile of Alexandre D Baffet including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 242
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Lindenhofer D, Haendeler S, Esk C, Littleboy J, Avalos C, Naas J, et al.
Nat Cell Biol . 2024 May; 26(5):710-718. PMID: 38714853
During brain development, neural progenitors expand through symmetric divisions before giving rise to differentiating cell types via asymmetric divisions. Transition between those modes varies among individual neural stem cells, resulting...
2.
Coquand L, Avalos C, Mace A, Farcy S, Di Cicco A, Lampic M, et al.
Nat Cell Biol . 2024 Mar; 26(5):698-709. PMID: 38548890
The human neocortex has undergone strong evolutionary expansion, largely due to an increased progenitor population, the basal radial glial cells. These cells are responsible for the production of a diversity...
3.
Wimmer R, Baffet A
Curr Opin Neurobiol . 2023 Apr; 80:102709. PMID: 37003105
A high number of genetic mutations associated with cortical malformations are found in genes coding for microtubule-related factors. This has stimulated research to understand how the various microtubule-based processes are...
4.
Brault J, Bardin S, Lampic M, Carpentieri J, Coquand L, Penisson M, et al.
EMBO Rep . 2022 Aug; 23(10):e54605. PMID: 35979738
Radial glial (RG) cells are the neural stem cells of the developing neocortex. Apical RG (aRG) cells can delaminate to generate basal RG (bRG) cells, a cell type associated with...
5.
Farcy S, Albert A, Gressens P, Baffet A, El Ghouzzi V
Cells . 2022 Jul; 11(14). PMID: 35883578
How the brain develops and achieves its final size is a fascinating issue that questions cortical evolution across species and man's place in the animal kingdom. Although animal models have...
6.
Carpentieri J, Di Cicco A, Lampic M, Andreau D, Del Maestro L, El Marjou F, et al.
Nat Commun . 2022 Jan; 13(1):16. PMID: 35013230
Primary microcephaly and megalencephaly are severe brain malformations defined by reduced and increased brain size, respectively. Whether these two pathologies arise from related alterations at the molecular level is unclear....
7.
Kyrousi C, ONeill A, Brazovskaja A, He Z, Kielkowski P, Coquand L, et al.
Nat Commun . 2021 Nov; 12(1):6298. PMID: 34728600
Basal progenitors (BPs), including intermediate progenitors and basal radial glia, are generated from apical radial glia and are enriched in gyrencephalic species like humans, contributing to neuronal expansion. Shortly after...
8.
Coquand L, Victoria G, Tata A, Carpentieri J, Brault J, Guimiot F, et al.
J Cell Biol . 2021 May; 220(8). PMID: 34019079
Neurons of the neocortex are generated by stem cells called radial glial cells. These polarized cells extend a short apical process toward the ventricular surface and a long basal fiber...
9.
Brault J, Khou C, Basset J, Coquand L, Fraisier V, Frenkiel M, et al.
EBioMedicine . 2016 Jul; 10:71-6. PMID: 27453325
The recent Zika outbreak in South America and French Polynesia was associated with an epidemic of microcephaly, a disease characterized by a reduced size of the cerebral cortex. Other members...
10.
Baffet A, Carabalona A, Dantas T, Doobin D, Hu D, Vallee R
Methods Cell Biol . 2016 Jan; 131:349-63. PMID: 26794523
Development of the cerebral cortex is a very dynamic process, involving a series of complex morphogenetic events. Following division of progenitor cells in the ventricular zone, neurons undergo a series...