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Alexandre Corthay

Explore the profile of Alexandre Corthay including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 1477
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Recent Articles
1.
Gilmour B, Corthay A, Oynebraten I
NPJ Vaccines . 2024 May; 9(1):83. PMID: 38702320
The cytokine IL-12p70 is crucial for T helper 1 (Th1) polarization and the generation of type 1 immunity required to fight cancer and pathogens. Therefore, strategies to optimize the production...
2.
Wold C, Christopoulos P, Arias M, Dzovor D, Oynebraten I, Corthay A, et al.
Commun Biol . 2024 Feb; 7(1):222. PMID: 38396285
Fungal polysaccharides can exert immunomodulating activity by triggering pattern recognition receptors (PRRs) on innate immune cells such as macrophages. Here, we evaluate six polysaccharides isolated from the medicinal fungus Inonotus...
3.
Anderson C, Bonney E, Mueller T, Corthay A, Havele C, Singh N, et al.
Scand J Immunol . 2023 Dec; 98(3):e13311. PMID: 38112131
This is a report from a one-week workshop held in Athens, Greece in July of 2022. The workshop aimed to identify emerging concepts relevant to the fundamentals of immune regulation...
4.
Eek Mariampillai A, Hauge S, Oynebraten I, Rodland G, Corthay A, Syljuasen R
Front Oncol . 2022 Nov; 12:981332. PMID: 36387237
Recent studies suggest that inhibition of the ATR kinase can potentiate radiation-induced antitumor immune responses, but the extent and mechanisms of such responses in human cancers remain scarcely understood. We...
5.
Corthay A, Hoglund P
Scand J Immunol . 2022 Apr; 95(5):e13173. PMID: 35474516
No abstract available.
6.
Frafjord A, Buer L, Hammarstrom C, Aamodt H, Woldbaek P, Brustugun O, et al.
Front Immunol . 2021 Dec; 12:764596. PMID: 34868011
Tumor-specific T helper (Th) cells have a central role in the immune response against cancer. However, there exist distinct Th cell subsets with very different and antagonizing properties. Some Th...
7.
Christopoulos P, Grigalavicius M, Corthay A, Berg K, Theodossiou T
Antioxidants (Basel) . 2021 Aug; 10(7). PMID: 34356382
Metabolic modulation of macrophage activation has emerged as a promising strategy lately in immunotherapeutics. However, macrophages have a broad spectrum of functions and thus, understanding the exact metabolic changes that...
8.
Corthay A, Bakacs T, Thangavelu G, Anderson C
Semin Cancer Biol . 2021 Feb; 78:5-16. PMID: 33582171
Disseminated non-dividing (dormant) cancer cells as well as those in equilibrium with the immune response remain the major challenge for successful treatment of cancer. The equilibrium between disseminated dormant cancer...
9.
Stankovic B, Aamodt H, Bjorhovde H, Muller E, Hammarstrom C, Brustugun O, et al.
Scand J Immunol . 2020 May; 92(2):e12893. PMID: 32433774
Pulmonary typical carcinoid (TC) is a low-grade, rare lung cancer of neuroendocrine origin. Currently, there is very little information available about the immune cell composition in TC tumours. Here, we...
10.
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al.
Commun Biol . 2020 Apr; 3(1):196. PMID: 32332858
The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint pathway blockade. Evidence for WNT/β-catenin signaling-mediated...