Alexandra Tassin
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Explore the profile of Alexandra Tassin including associated specialties, affiliations and a list of published articles.
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20
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822
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Recent Articles
1.
Nguyen T, Limpens M, Bouhmidi S, Paprzycki L, Legrand A, Decleves A, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542301
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent inherited muscle disorders and is linked to the inappropriate expression of the DUX4 transcription factor in skeletal muscles. The deregulated...
2.
Nguyen T, Paprzycki L, Legrand A, Decleves A, Heher P, Limpens M, et al.
Skelet Muscle
. 2023 Dec;
13(1):21.
PMID: 38104132
Background: Hypoxia is known to modify skeletal muscle biological functions and muscle regeneration. However, the mechanisms underlying the effects of hypoxia on human myoblast differentiation remain unclear. The hypoxic response...
3.
Claus C, Slavin M, Ansseau E, Lancelot C, Bah K, Lassche S, et al.
Skelet Muscle
. 2023 Mar;
13(1):5.
PMID: 36882853
Background: We have previously demonstrated that double homeobox 4 centromeric (DUX4C) encoded for a functional DUX4c protein upregulated in dystrophic skeletal muscles. Based on gain- and loss-of-function studies we have...
4.
Heher P, Ganassi M, Weidinger A, Engquist E, Pruller J, Nguyen T, et al.
Redox Biol
. 2022 Mar;
51:102251.
PMID: 35248827
Facioscapulohumeral muscular dystrophy (FSHD) is characterised by descending skeletal muscle weakness and wasting. FSHD is caused by mis-expression of the transcription factor DUX4, which is linked to oxidative stress, a...
5.
Nguyen T, Conotte S, Belayew A, Decleves A, Legrand A, Tassin A
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34281273
Muscular dystrophies (MDs) are a group of inherited degenerative muscle disorders characterized by a progressive skeletal muscle wasting. Respiratory impairments and subsequent hypoxemia are encountered in a significant subgroup of...
6.
Juszczak F, Vlassembrouck M, Botton O, Zwakhals T, Decarnoncle M, Tassin A, et al.
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33396267
Exercise training is now recognized as an interesting therapeutic strategy in managing obesity and its related disorders. However, there is still a lack of knowledge about its impact on obesity-induced...
7.
Pierard M, Tassin A, Legrand A, Legrand A
BMC Pulm Med
. 2020 Oct;
20(1):255.
PMID: 32998721
Background: Disease progression in COPD patient is associated to lung function decline, leading to a higher risk of hypoxaemia and associated comorbidities, notably cardiovascular diseases (CVD). Adiponectin (Ad) is an...
8.
Derenne A, Tassin A, Nguyen T, De Roeck E, Jenart V, Ansseau E, et al.
Sci Rep
. 2020 Jul;
10(1):11301.
PMID: 32647247
Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector injection for transgene expression into skeletal muscles. In this study, IMEP was...
9.
Pierard M, Tassin A, Conotte S, Boudjeltia K, Legrand A
Front Physiol
. 2019 Feb;
10:68.
PMID: 30800074
Hypoxemia is a critical component of several respiratory diseases and is known to be involved in the processes underlying co-morbidities associated to such disorders, notably at the cardiovascular level. Circulating...
10.
Conotte S, Tassin A, Conotte R, Colet J, Boudjeltia K, Legrand A
Respir Physiol Neurobiol
. 2018 Mar;
256:157-173.
PMID: 29522877
Chronic intermittent hypoxia (ChIH) is a dominant feature of obstructive sleep apnoea (OSA) and is associated to metabolic alterations and oxidative stress (OS). Although management of OSA is well established,...