Alexandra Stolzing
Overview
Explore the profile of Alexandra Stolzing including associated specialties, affiliations and a list of published articles.
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69
Citations
2456
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Recent Articles
1.
Lyu Y, Fu Q, Wilczok D, Ying K, King A, Antebi A, et al.
Aging (Albany NY)
. 2024 Oct;
16(20):12955-12976.
PMID: 39418098
The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We,...
2.
Frost O, Ramkilawan P, Rebbaa A, Stolzing A
Ageing Res Rev
. 2024 Apr;
97:102295.
PMID: 38588866
Organismal aging involves the progressive decline in organ function and increased susceptibility to age-associated diseases. Regardless of its origin, cellular aging is consequently reflected at the level of organ and...
3.
Admasu T, Kim K, Rae M, Avelar R, Gonciarz R, Rebbaa A, et al.
Cell Rep
. 2023 Feb;
42(2):112058.
PMID: 36753419
Senescent cells can spread the senescent phenotype to other cells by secreting senescence-associated secretory phenotype factors. The resulting paracrine senescent cells make a significant contribution to the burden of senescent...
4.
Brauning A, Rae M, Zhu G, Fulton E, Admasu T, Stolzing A, et al.
Cells
. 2022 Mar;
11(6).
PMID: 35326467
Aging is the greatest risk factor for nearly all major chronic diseases, including cardiovascular diseases, cancer, Alzheimer's and other neurodegenerative diseases of aging. Age-related impairment of immune function (immunosenescence) is...
5.
Kim K, Admasu T, Stolzing A, Sharma A
Aging (Albany NY)
. 2022 Mar;
14(5):2131-2147.
PMID: 35245208
In the context of aging and age-associated diseases, Natural Killer (NK) cells have been revealed as a key cell type responsible for the immune clearance of senescent cells. Subsequently, NK...
6.
Saravanan S, Lewis C, Dixit B, OConnor M, Stolzing A, Boominathan A
Biomedicines
. 2022 Feb;
10(2).
PMID: 35203698
Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular...
7.
Olgasi C, Borsotti C, Merlin S, Bergmann T, Bittorf P, Adewoye A, et al.
Mol Ther Methods Clin Dev
. 2021 Dec;
23:551-566.
PMID: 34853801
Hemophilia A (HA) is a rare bleeding disorder caused by deficiency/dysfunction of the FVIII protein. As current therapies based on frequent FVIII infusions are not a definitive cure, long-term expression...
8.
Admasu T, Rae M, Stolzing A
Ageing Res Rev
. 2021 Jul;
70:101412.
PMID: 34302996
Cellular senescence is a state of stable cell cycle arrest that is known to be elicited in response to different stresses or forms of damage. Senescence limits the replication of...
9.
Wragg N, Tampakis D, Stolzing A
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33203028
Mesenchymal stem cells (MSCs) can differentiate into multiple different tissue lineages and have favourable immunogenic potential making them an attractive prospect for regenerative medicine. As an essential part of the...
10.
Adewoye A, Tampakis D, Follenzi A, Stolzing A
Biogerontology
. 2020 Aug;
21(6):773-786.
PMID: 32776262
It has been over half a century since cellular senescence was first noted and characterized, and yet no consensus senescent marker has been reliably established. This challenge is compounded by...