Alexandra O S Cunha
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Explore the profile of Alexandra O S Cunha including associated specialties, affiliations and a list of published articles.
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8
Citations
33
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Recent Articles
1.
Mortari M, Cunha A, Dos Anjos L, Amaral H, Quintanilha M, Gelfuso E, et al.
Brain Commun
. 2023 Feb;
5(1):fcad016.
PMID: 36844150
The ability of venom-derived peptides to disrupt physiological processes in mammals provides an exciting source for pharmacological development. Our research group has identified a new class of neuroactive peptides from...
2.
Wolf D, Sanon N, Cunha A, Chen J, Shaker T, Elhassan A, et al.
Sci Rep
. 2022 Feb;
12(1):3186.
PMID: 35210456
Sexual differentiation of the brain is influenced by testosterone and its metabolites during the perinatal period, when many aspects of brain development, including the maturation of GABAergic transmission, occur. Whether...
3.
Lazarini-Lopes W, Do Val-da Silva R, da Silva-Junior R, Cunha A, Garcia-Cairasco N
Front Behav Neurosci
. 2021 Mar;
15:611902.
PMID: 33643007
Cannabinoids and -derived compounds have been receiving especial attention in the epilepsy research scenario. Pharmacological modulation of endocannabinoid system's components, like cannabinoid type 1 receptors (CB1R) and their bindings, are...
4.
Gelfuso E, Reis S, Aguiar D, Faggion S, Gomes F, Galan D, et al.
Eur J Pharmacol
. 2020 Aug;
885:173390.
PMID: 32735983
Erythrinian alkaloids ((+)-erythravine and (+)-11-α-hydroxy-erythravine) have been pointed as the main responsible agents for the anticonvulsant and anxiolytic properties of Erythrina mulungu Mart ex Benth. The present work provides a...
5.
Fachim H, Guizzo R, Cunha A, Pereira A, Dos Anjos L, Mortari M, et al.
J Biochem Mol Toxicol
. 2020 Jul;
34(11):e22578.
PMID: 32666660
β-Lactam antibiotics such as ceftriaxone, are potent stimulators of the expression of l-glutamate transporter GLT-1 and may exert neuroprotective effects when chronically used in rats and mice. In this study,...
6.
de Deus J, Amorim M, Ribeiro A, Barcellos-Filho P, Ceballos C, Branco L, et al.
Cell Mol Neurobiol
. 2020 May;
41(4):751-763.
PMID: 32445041
Exposure to noise produces cognitive and emotional disorders, and recent studies have shown that auditory stimulation or deprivation affects hippocampal function. Previously, we showed that exposure to high-intensity sound (110 ...
7.
Cunha A, de Deus J, Ceballos C, Leao R
PLoS One
. 2019 May;
14(5):e0210451.
PMID: 31067215
Exposure to loud sounds is related to harmful mental and systemic effects. The hippocampal function can be affected to either high-intensity sound exposure or long-term sound deprivation. We previously showed...
8.
Gelfuso E, Liberato J, Cunha A, Mortari M, Beleboni R, Lopes N, et al.
Neurosci Lett
. 2013 Apr;
543:12-6.
PMID: 23562887
The aims of the present work were to investigate the effects of the repeated administration of Parawixin2 (2-amino-5-ureidopentanamide; formerly FrPbAII), a novel GABA and glycine uptake inhibitor, in rats submitted...