Alexandra N Brown-Suedel
Overview
Explore the profile of Alexandra N Brown-Suedel including associated specialties, affiliations and a list of published articles.
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5
Citations
47
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Recent Articles
1.
Sakthivel D, Brown-Suedel A, Lopez K, Salgar S, Coutinho L, Keane F, et al.
Sci Adv
. 2024 Aug;
10(31):eadj3145.
PMID: 39093977
Mutation in nucleophosmin (NPM1) causes relocalization of this normally nucleolar protein to the cytoplasm (NPM1c+). Despite NPM1 mutation being the most common driver mutation in cytogenetically normal adult acute myeloid...
2.
Brown-Suedel A, Bouchier-Hayes L
EMBO J
. 2023 Sep;
42(20):e115307.
PMID: 37691515
Removal of polyploid cells is essential to preventing cancer and restricting tumor growth. A new study published in The EMBO Journal shows assembly of the NEMO-PIDDosome on extra centrioles. Activation...
3.
Sakthivel D, Brown-Suedel A, Keane F, Huang S, Sherry K, Charendoff C, et al.
bioRxiv
. 2023 Jul;
PMID: 37398413
Mutation in nucleophosmin (NPM1) causes relocalization of this normally nucleolar protein to the cytoplasm ( ). Despite NPM1 mutation being the most common driver mutation in cytogenetically normal adult acute...
4.
Bolivar B, Brown-Suedel A, Rohrman B, Charendoff C, Yazdani V, Belcher J, et al.
J Immunol
. 2021 Mar;
206(8):1878-1889.
PMID: 33741688
Excessive release of heme from RBCs is a key pathophysiological feature of several disease states, including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level...
5.
Brown-Suedel A, Bouchier-Hayes L
Front Cell Dev Biol
. 2021 Jan;
8:610022.
PMID: 33425918
Caspase-2 belongs to the caspase family of proteins responsible for essential cellular functions including apoptosis and inflammation. Uniquely, caspase-2 has been identified as a tumor suppressor, but how it regulates...