Alexandra Lauric
Overview
Explore the profile of Alexandra Lauric including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
292
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Recent Articles
1.
Lauric A, Ludwig C, Malek A
Neurosurgery
. 2023 Jun;
93(6):1285-1295.
PMID: 37387576
Background And Objectives: Topological data analysis (TDA), which identifies patterns in data through simplified topological signatures, has yet to be applied to aneurysm research. We investigate TDA Mapper graphs (Mapper)...
2.
Lauric A, Ludwig C, Malek A
World Neurosurg
. 2021 Nov;
159:e8-e22.
PMID: 34823040
Background: Radiomics is a powerful tool for automatic extraction of morphological features, but when applied to cerebral aneurysms, it is inferior to established descriptors in classifying rupture status. We sought...
3.
Lauric A, Hippelheuser J, Malek A
World Neurosurg
. 2021 Nov;
158:e334-e343.
PMID: 34740832
Background: Wall shear stress (WSS), the spatial gradient of flow velocity at luminal surface, has been employed for aneurysmal hemodynamic analysis, but it is sensitive to surface irregularities and noise....
4.
Malek A, Hippelheuser J, Lauric A
J Neurosurg
. 2021 Oct;
136(6):1726-1737.
PMID: 34715656
Objective: Aneurysm formation preferentially occurs at the site of wide-angle cerebral arterial bifurcations, which were recently shown to have a high longitudinal positive wall shear stress (WSS) gradient that promotes...
5.
Lauric A, Silveira L, Lesha E, Breton J, Malek A
J Neurosurg
. 2021 Oct;
136(6):1694-1704.
PMID: 34653994
Objective: Vessel tapering results in blood flow acceleration at downstream bifurcations (firehose nozzle effect), induces hemodynamics predisposing to aneurysm initiation, and has been associated with middle cerebral artery (MCA) aneurysm...
6.
Ludwig C, Lauric A, Malek J, Mulligan R, Malek A
J Neurointerv Surg
. 2020 Nov;
13(8):755-761.
PMID: 33158993
Background: Morphological differences between ruptured and unruptured cerebral aneurysms represent a focus of neuroimaging researchfor understanding the mechanisms of aneurysmal rupture. We evaluated the performance of Radiomics derived morphological features,...
7.
Rosato R, Comptdaer G, Mulligan R, Breton J, Lesha E, Lauric A, et al.
J Neurointerv Surg
. 2020 May;
12(11):1142-1147.
PMID: 32447300
Background: Aneurysms at the posterior communicating artery (PCOM) origin represent the most common location on the internal carotid artery (ICA), and are associated with greater recurrence following endovascular treatment. We...
8.
Lauric A, Hippelheuser J, Malek A
J Neurosurg
. 2018 Aug;
131(2):442-452.
PMID: 30095336
Objective: Endothelium adapts to wall shear stress (WSS) and is functionally sensitive to positive (aneurysmogenic) and negative (protective) spatial WSS gradients (WSSG) in regions of accelerating and decelerating flow, respectively....
9.
Lauric A, Greim-Kuczewski K, Antonov A, Dardik G, Magida J, Hippelheuser J, et al.
Neurosurgery
. 2018 May;
84(5):1082-1089.
PMID: 29846722
Background: Cerebral aneurysm initiation and evolution have been linked to hemodynamic and morphological factors. Stenotic morphology upstream to a bifurcation can alter hemodynamic patterns and lead to destructive vessel wall...
10.
Almasi S, Lauric A, Malek A, Miller E
Med Image Anal
. 2018 Mar;
46:118-129.
PMID: 29518676
Registration of vascular networks is an indispensable element of prognostic and diagnostic studies that require structural analysis and comparison over time, among different samples, and to a gold standard. However,...