Alexandra L Joyner
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Explore the profile of Alexandra L Joyner including associated specialties, affiliations and a list of published articles.
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101
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6781
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Recent Articles
1.
Lee A, Arefin T, Gubanova A, Stephen D, Liu Y, Lao Z, et al.
Nat Commun
. 2025 Feb;
16(1):1858.
PMID: 39984491
The capacity of the brain to compensate for insults during development depends on the type of cell loss, whereas the consequences of genetic mutations in the same neurons are difficult...
2.
Joyner A, Ortigao-Farias J, Kornberg T
Development
. 2024 Dec;
151(24).
PMID: 39671171
More than 40 years ago, studies of the Drosophila engrailed and Hox genes led to major discoveries that shaped the history of developmental biology. We learned that these genes define...
3.
Pakula A, El Nagar S, Bayin N, Christensen J, Stephen D, Reid A, et al.
bioRxiv
. 2024 Oct;
PMID: 39464104
The neonatal mouse cerebellum shows remarkable regenerative potential upon injury at birth, wherein a subset of Nestin-expressing progenitors (NEPs) undergoes adaptive reprogramming to replenish granule cell progenitors that die. Here,...
4.
Lee A, Arefin T, Gubanova A, Stephen D, Liu Y, Lao Z, et al.
bioRxiv
. 2024 Jul;
PMID: 39026865
The capacity of the brain to compensate for insults during development depends on the type of cell loss, whereas the consequences of genetic mutations in the same neurons are difficult...
5.
Krishnamurthy A, Lee A, Bayin N, Stephen D, Nasef O, Lao Z, et al.
Development
. 2024 Jun;
151(14).
PMID: 38912572
The neurons of the three cerebellar nuclei (CN) are the primary output neurons of the cerebellum. The excitatory neurons (e) of the medial (m) CN (eCNm) were recently divided into...
6.
Yamada M, Keller R, Gutierrez R, Cameron D, Suzuki H, Sanghrajka R, et al.
Sci Adv
. 2024 Mar;
10(12):eadn4649.
PMID: 38517960
Genomic rearrangements are a hallmark of most childhood tumors, including medulloblastoma, one of the most common brain tumors in children, but their causes remain largely unknown. Here, we show that...
7.
Cook A, Bishop T, Crowe H, Stevens D, Reine L, Joyner A, et al.
Development
. 2024 Jan;
151(3).
PMID: 38251865
Modeling has led to proposals that the amount of neural tissue folding is set by the level of differential expansion between tissue layers and that the wavelength is set by...
8.
Krishnamurthy A, Lee A, Bayin N, Stephen D, Nasef O, Lao Z, et al.
bioRxiv
. 2023 Dec;
PMID: 38077070
The excitatory neurons of the three cerebellar nuclei (eCN) form the primary output for the cerebellar circuit. The medial eCN (eCNm) were recently divided into molecularly defined subdomains in the...
9.
Sanghrajka R, Koche R, Medrano H, El Nagar S, Stephen D, Lao Z, et al.
iScience
. 2023 Oct;
26(10):107831.
PMID: 37822508
The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB)...
10.
Cook A, Bishop T, Crowe H, Stevens D, Reine L, Joyner A, et al.
bioRxiv
. 2023 Jul;
PMID: 37503300
Modeling has proposed that the amount of neural tissue folding is set by the level of differential-expansion between tissue layers and that the wavelength is set by the thickness of...