Alexandra Kueider-Paisley
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Explore the profile of Alexandra Kueider-Paisley including associated specialties, affiliations and a list of published articles.
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14
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Recent Articles
1.
Borkowski K, Liang N, Zhao N, Arnold M, Huynh K, Karu N, et al.
bioRxiv
. 2025 Mar;
PMID: 40060656
Alzheimer's disease (AD) risk and progression are significantly influenced by APOE genotype with APOE4 increasing and APOE2 decreasing susceptibility compared to APOE3. While the effect of those genotypes was extensively...
2.
Chen T, Wang L, Xie G, Kristal B, Zheng X, Sun T, et al.
Adv Sci (Weinh)
. 2023 Dec;
11(9):e2306576.
PMID: 38093507
Sex disparities in serum bile acid (BA) levels and Alzheimer's disease (AD) prevalence have been established. However, the precise link between changes in serum BAs and AD development remains elusive....
3.
Ko Y, Billheimer J, Lyssenko N, Kueider-Paisley A, Wolk D, Arnold S, et al.
Alzheimers Res Ther
. 2022 Dec;
14(1):194.
PMID: 36572909
Background: Alzheimer's disease (AD) shares risk factors with cardiovascular disease (CVD) and dysregulated cholesterol metabolism is a mechanism common to both diseases. Cholesterol efflux capacity (CEC) is an ex vivo...
4.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, et al.
Commun Biol
. 2022 Oct;
5(1):1074.
PMID: 36209301
Dysregulation of sphingomyelin and ceramide metabolism have been implicated in Alzheimer's disease. Genome-wide and transcriptome-wide association studies have identified various genes and genetic variants in lipid metabolism that are associated...
5.
Chang R, Trushina E, Zhu K, Zaidi S, Lau B, Kueider-Paisley A, et al.
Alzheimers Dement
. 2022 Apr;
19(2):518-531.
PMID: 35481667
Introduction: Late-onset Alzheimer's disease (LOAD) is a complex neurodegenerative disease characterized by multiple progressive stages, glucose metabolic dysregulation, Alzheimer's disease (AD) pathology, and inexorable cognitive decline. Discovery of metabolic profiles...
6.
Nho K, Kueider-Paisley A, Arnold M, Mahmoudiandehkordi S, Risacher S, Louie G, et al.
Brain Commun
. 2021 Aug;
3(3):fcab139.
PMID: 34396103
Metabolomics in the Alzheimer's Disease Neuroimaging Initiative cohort provides a powerful tool for mapping biochemical changes in Alzheimer's disease, and a unique opportunity to learn about the association between circulating...
7.
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease
Baloni P, Funk C, Yan J, Yurkovich J, Kueider-Paisley A, Nho K, et al.
Cell Rep Med
. 2020 Dec;
1(8):100138.
PMID: 33294859
Increasing evidence suggests Alzheimer's disease (AD) pathophysiology is influenced by primary and secondary bile acids, the end product of cholesterol metabolism. We analyze 2,114 post-mortem brain transcriptomes and identify genes...
8.
Wang J, Wei R, Xie G, Arnold M, Kueider-Paisley A, Louie G, et al.
Sci Rep
. 2020 Aug;
10(1):14059.
PMID: 32820198
The incidence of Alzheimer's disease (AD) increases with age and is becoming a significant cause of worldwide morbidity and mortality. However, the metabolic perturbation behind the onset of AD remains...
9.
Kling M, Goodenowe D, Senanayake V, Mahmoudiandehkordi S, Arnold M, Massaro T, et al.
Alzheimers Dement
. 2020 Jul;
16(9):1234-1247.
PMID: 32715599
Introduction: Altered lipid metabolism is implicated in Alzheimer's disease (AD), but the mechanisms remain obscure. Aging-related declines in circulating plasmalogens containing omega-3 fatty acids may increase AD risk by reducing...
10.
Zhao N, Ren Y, Yamazaki Y, Qiao W, Li F, Felton L, et al.
Neuron
. 2020 Mar;
106(5):727-742.e6.
PMID: 32199103
Evidence suggests interplay among the three major risk factors for Alzheimer's disease (AD): age, APOE genotype, and sex. Here, we present comprehensive datasets and analyses of brain transcriptomes and blood...