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Alexandra Koch

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Articles 33
Citations 348
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Recent Articles
1.
Coors A, Boenniger M, Santos M, Lohner V, Koch A, Ettinger U, et al.
Neurology . 2025 Feb; 104(6):e210278. PMID: 39977717
Background And Objectives: Plasma neurofilament light chain (NfL) level is a sensitive yet aspecific marker of neurodegeneration. Its neuroanatomical and functional correlates in the general population are not fully elucidated....
2.
Alaeddin N, Koch A, Etteldorf R, Stingl J, Breteler M, de Vries F
Sci Rep . 2024 Dec; 14(1):30486. PMID: 39681582
Reports linking proton pump inhibitors (PPIs) with cognition and dementia show conflicting results, with limited evidence on underlying biological mechanisms. However, existing studies did not investigate brain microstructure, which could...
3.
Koch A, Stirnberg R, Estrada S, Zeng W, Lohner V, Shahid M, et al.
Nat Protoc . 2024 Dec; PMID: 39672917
Neuroimaging has an essential role in studies of brain health and of cerebrovascular and neurodegenerative diseases, requiring the availability of versatile magnetic resonance imaging (MRI) acquisition and processing protocols. We...
4.
Ewert C, Kugler D, Stirnberg R, Koch A, Yendiki A, Reuter M
Imaging Neurosci (Camb) . 2024 Nov; 2:1-18. PMID: 39575177
Diffusion-weighted magnetic resonance imaging (dMRI) permits a detailed in-vivo analysis of neuroanatomical microstructure, invaluable for clinical and population studies. However, many measurements with different diffusion-encoding directions and possibly -values are...
5.
Galante H, De Agro M, Koch A, Kau S, Czaczkes T
iScience . 2024 Jul; 27(6):109935. PMID: 39055608
Argentine ants, , are a particularly concerning invasive species. Control efforts often fall short likely due to a lack of sustained bait consumption. Using neuroactives, such as caffeine, to improve...
6.
Le Grand Q, Tsuchida A, Koch A, Imtiaz M, Aziz N, Vigneron C, et al.
Mol Psychiatry . 2024 May; 29(11):3567-3579. PMID: 38811690
Cerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Genetic risk loci for white matter hyperintensities (WMH), the most common MRI-marker of cSVD in older age,...
7.
Garzone D, Finger R, Mauschitz M, Koch A, Reuter M, Breteler M, et al.
Hum Brain Mapp . 2023 Feb; 44(7):2701-2711. PMID: 36852616
Visual impairment and retinal neurodegeneration are intrinsically connected and both have been associated with cognitive impairment and brain atrophy, but the underlying mechanisms remain unclear. To investigate whether transneuronal degeneration...
8.
Mauschitz M, Lohner V, Koch A, Stocker T, Reuter M, Holz F, et al.
Sci Rep . 2022 Feb; 12(1):2757. PMID: 35177781
Retinal assessments have been discussed as biomarkers for brain atrophy. However, available studies did not investigate all retinal layers due to older technology, reported inconsistent results, or were based on...
9.
Czaczkes T, Berger A, Koch A, Dreisbach G
J Comp Psychol . 2021 Oct; 136(1):35-43. PMID: 34694823
Response conflicts occur when the correct goal-congruent response is weaker than an alternative but incorrect response. To overcome response conflicts, the stronger response has to be inhibited, making the study...
10.
Konieczny M, Dewenter A, Ter Telgte A, Gesierich B, Wiegertjes K, Finsterwalder S, et al.
Neurology . 2020 Nov; 96(5):e698-e708. PMID: 33199431
Objective: To test the hypothesis that multi-shell diffusion models improve the characterization of microstructural alterations in cerebral small vessel disease (SVD), we assessed associations with processing speed performance, longitudinal change,...