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Alexandra Junza

Explore the profile of Alexandra Junza including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 344
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Recent Articles
1.
Gimenez-Lopez J, Jimenez-Murcia J, Junza A, Minguillon C, Barron D
J Agric Food Chem . 2024 May; 72(23):13393-13401. PMID: 38809443
The high standards required for food safety make it necessary to trace unambiguously raw or cooked food products coming from medicated animals. Nevertheless, considering the lability of β-lactams and their...
2.
Girona J, Soler O, Samino S, Junza A, Martinez-Micaelo N, Garcia-Altares M, et al.
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38473949
Ectopic fat accumulation in non-adipose tissues is closely related to diabetes-related myocardial dysfunction. Nevertheless, the complete picture of the lipid metabolites involved in the metabolic-related myocardial alterations is not fully...
3.
Kovatcheva M, Melendez E, Chondronasiou D, Pietrocola F, Bernad R, Caballe A, et al.
Nat Metab . 2023 Nov; 5(11):1911-1930. PMID: 37973897
Transient reprogramming by the expression of OCT4, SOX2, KLF4 and MYC (OSKM) is a therapeutic strategy for tissue regeneration and rejuvenation, but little is known about its metabolic requirements. Here...
4.
Julve J, Genua I, Quifer-Rada P, Yanes O, Barranco-Altirriba M, Hernandez M, et al.
Diabetes Res Clin Pract . 2023 Feb; 197:110578. PMID: 36804334
Aims: To uncover novel candidate metabolomic and lipidomic biomarkers in newly-diagnosed type 1 diabetes (T1DM) after achieving optimal glucose control. Methods: Comprehensive lipidomic and metabolomic analysis was performed in serum...
5.
Canyelles M, Perez A, Junza A, Minambres I, Yanes O, Sarda H, et al.
Diagnostics (Basel) . 2022 Nov; 12(11). PMID: 36428843
High circulating concentrations of the gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) are significantly associated with the risk of obesity and type 2 diabetes (T2D). We aimed at evaluating the impact...
6.
Junza A, Saurina J, Minguillon C, Barron D
J Agric Food Chem . 2022 Jul; 70(27):8441-8450. PMID: 35776853
In this work, metabolomic profile changes in milk from cows affected by mastitis and treated with enrofloxacin (ENR) have been studied using LC-HRMS techniques. Principal component analysis was applied to...
7.
Dutto I, Gerhards J, Herrera A, Souckova O, Skopova V, Smak J, et al.
Elife . 2022 Feb; 11. PMID: 35133277
Adenylosuccinate lyase (ADSL) functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. ADSL deficiency (ADSLD) causes numerous neurodevelopmental pathologies, including microcephaly and autism spectrum disorder. ADSLD patients...
8.
Canyelles M, Garcia-Osuna A, Junza A, Yanes O, Puig N, Ordonez-Llanos J, et al.
Biomedicines . 2021 Oct; 9(10). PMID: 34680453
Impaired HDL-mediated macrophage cholesterol efflux and higher circulating concentrations of trimethylamine N-oxide (TMAO) levels are independent risk factors for cardiovascular mortality. The TMAO precursors, γ-butyrobetaine (γBB) and Trimethyllysine (TML), have...
9.
Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L, et al.
Cell Rep . 2021 Aug; 36(8):109565. PMID: 34433037
Mitochondria constantly undergo fusion and fission events, referred as mitochondrial dynamics, which determine mitochondrial architecture and bioenergetics. Cultured cell studies demonstrate that mitochondrial dynamics are acutely regulated by phosphorylation of...
10.
Herranz C, Mateo F, Baiges A, Ruiz de Garibay G, Junza A, Johnson S, et al.
EMBO Mol Med . 2021 Aug; 13(9):e13929. PMID: 34378323
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis...