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Alexandra Ingendoh-Tsakmakidis

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Articles 12
Citations 78
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Recent Articles
1.
Heine N, Doll-Nikutta K, Stein F, Jakobi J, Ingendoh-Tsakmakidis A, Rehbock C, et al.
Sci Rep . 2024 Feb; 14(1):3405. PMID: 38336925
Staphylococcus aureus biofilm-associated infections are a common complication in modern medicine. Due to inherent resilience of biofilms to antibiotics and the rising number of antibiotic-resistant bacterial strains, new treatment options...
2.
Streich C, Stein F, Jakobi J, Ingendoh-Tsakmakidis A, Heine N, Rehbock C, et al.
Adv Healthc Mater . 2023 Sep; 12(30):e2302084. PMID: 37661312
The bactericidal effects of silver nanoparticles (Ag NPs) against infectious strains of multiresistant bacteria is a well-studied phenomenon, highly relevant for many researchers and clinicians battling bacterial infections. However, little...
3.
Miliotou A, Foltopoulou P, Ingendoh-Tsakmakidis A, Tsiftsoglou A, Vizirianakis I, Pappas I, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678915
Mitochondrial disorders represent a heterogeneous group of genetic disorders with variations in severity and clinical outcomes, mostly characterized by respiratory chain dysfunction and abnormal mitochondrial function. More specifically, mutations in...
4.
Rahim M, Winkel A, Ingendoh-Tsakmakidis A, Lienenklaus S, Falk C, Eisenburger M, et al.
Biomedicines . 2022 Feb; 10(2). PMID: 35203495
Cytokine profiles are often perturbed after infections of medical implants. With a non-invasive imaging system, we report in a mouse model that interferon expression after infection of subcutaneous implants with...
5.
Mikolai C, Branitzki-Heinemann K, Ingendoh-Tsakmakidis A, Stiesch M, von Kockritz-Blickwede M, Winkel A
J Oral Microbiol . 2021 Jan; 13(1):1856565. PMID: 33391628
Oral innate immunity is led by neutrophils. It is still unclear how their main antimicrobial mechanisms against different biofilms may contribute to balance or dysregulation in the oral cavity. We...
6.
Schaeske J, Fadeeva E, Schlie-Wolter S, Deiwick A, Chichkov B, Ingendoh-Tsakmakidis A, et al.
Int J Mol Sci . 2020 Nov; 21(22). PMID: 33182746
Cytocompatibility is essential for implant approval. However, initial in vitro screenings mainly include the quantity of adherent immortalized cells and cytotoxicity. Other vital parameters, such as cell migration and an...
7.
Ingendoh-Tsakmakidis A, Eberhard J, Falk C, Stiesch M, Winkel A
Cells . 2020 May; 9(5). PMID: 32429151
Human gingival epithelial cells (HGEps) and fibroblasts (HGFs) are the main cell types in peri-implant soft tissue. HGEps are constantly exposed to bacteria, but HGFs are protected by connective tissue...
8.
Mikolai C, Kommerein N, Ingendoh-Tsakmakidis A, Winkel A, Falk C, Stiesch M
Cell Microbiol . 2020 Apr; 22(8):e13209. PMID: 32329166
The host-microbe relationship is pivotal for oral health as well as for peri-implant diseases. Peri-implant mucosa and commensal biofilm play important roles in the maintenance of host-microbe homeostasis, but little...
9.
Rahim M, Szafranski S, Ingendoh-Tsakmakidis A, Stiesch M, Mueller P
Colloids Surf B Biointerfaces . 2019 Dec; 186:110684. PMID: 31812076
Infections of medical implants caused by bacterial biofilms are a major clinical problem. Bacterial colonization is predicted to be prevented by alkaline magnesium surfaces. However, in experimental animal studies, magnesium...
10.
Ingendoh-Tsakmakidis A, Mikolai C, Winkel A, Szafranski S, Falk C, Rossi A, et al.
Cell Microbiol . 2019 Jul; 21(10):e13078. PMID: 31270923
The impact of oral commensal and pathogenic bacteria on peri-implant mucosa is not well understood, despite the high prevalence of peri-implant infections. Hence, we investigated responses of the peri-implant mucosa...