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Alexandra Gampel

Explore the profile of Alexandra Gampel including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 267
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Recent Articles
1.
Ward D, Carter D, Homer M, Marucci L, Gampel A
Haematologica . 2015 Nov; 101(3):286-96. PMID: 26589912
Erythropoietin is essential for the production of mature erythroid cells, promoting both proliferation and survival. Whether erythropoietin and other cytokines can influence lineage commitment of hematopoietic stem and progenitor cells...
2.
Satchwell T, Pellegrin S, Bianchi P, Hawley B, Gampel A, Mordue K, et al.
Haematologica . 2013 Aug; 98(11):1788-96. PMID: 23935019
Congenital dyserythropoietic anemia type II is an autosomally recessive form of hereditary anemia caused by SEC23B gene mutations. Patients exhibit characteristic phenotypes including multinucleate erythroblasts, erythrocytes with hypoglycosylated membrane proteins...
3.
Anstee D, Gampel A, Toye A
Curr Opin Hematol . 2012 Mar; 19(3):163-9. PMID: 22406823
Purpose Of Review: The present article reviews the recent data concerning the generation of red blood cells from haematopoietic stem cells using laboratory culture and discusses the potential for generating...
4.
Jones M, Caswell P, Moran-Jones K, Roberts M, Barry S, Gampel A, et al.
Traffic . 2009 Mar; 10(6):754-66. PMID: 19302266
The cell's main receptor for VEGF, VEGFR2 (Kdr) is one of the most important positive regulators of new blood vessel growth and its downstream signalling is well characterized. By contrast,...
5.
Zubcevic J, Waki H, Diez-Freire C, Gampel A, Raizada M, Paton J
Hypertension . 2008 Nov; 53(1):97-103. PMID: 19015400
Phosphatidylinositol 3-kinase (PI3K) within brain stem neurons has been implicated in hypertension in the spontaneously hypertensive rat (SHR). Previously, we demonstrated elevated expression of PI3K subunits in rostral ventrolateral medulla...
6.
Gampel A, Moss L, Jones M, Brunton V, Norman J, Mellor H
Blood . 2006 Apr; 108(8):2624-31. PMID: 16638931
Endothelial cells respond to vascular endothelial growth factor (VEGF) to produce new blood vessels. This process of angiogenesis makes a critical contribution during embryogenesis and also in the response to...
7.
Wherlock M, Gampel A, Futter C, Mellor H
J Cell Sci . 2004 Jul; 117(Pt 15):3221-31. PMID: 15226397
The Rho family of small GTPases play a pivotal role in the dynamic regulation of the actin cytoskeleton. Recent studies have suggested that these signalling proteins also have wide-ranging functions...
8.
Gampel A, Mellor H
Biochem J . 2002 Jul; 366(Pt 2):393-8. PMID: 12113653
Rho GTPases control a complex network of intracellular signalling pathways. Whereas progress has been made in identifying downstream signalling partners for these proteins, the characterization of Rho upstream regulatory guanine-nucleotide...
9.
Sudarsan V, Pasalodos-Sanchez S, Wan S, Gampel A, Skaer H
Development . 2002 Feb; 129(4):935-44. PMID: 11861476
Cell proliferation in the developing renal tubules of Drosophila is strikingly patterned, occurring in two phases to generate a consistent number of tubule cells. The later phase of cell division...