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Alexandra C Gillett

Explore the profile of Alexandra C Gillett including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kamp M, Lo C, Kokkinidis G, Chauhan M, Gillett A, McIntosh A, et al.
Psychol Med . 2025 Mar; 55:e80. PMID: 40071563
Background: In major depressive disorder (MDD), only ~35% achieve remission after first-line antidepressant therapy. Using UK Biobank data, we identify sociodemographic, clinical, and genetic predictors of antidepressant response through self-reported...
2.
Gillett A, Hagenaars S, Handley D, Casanova F, Young K, Green H, et al.
BMC Med . 2024 May; 22(1):211. PMID: 38807170
Background: This study evaluates longitudinal associations between glycaemic control, measured by mean and within-patient variability of glycated haemaglobin (HbA1c) levels, and major depressive disorder (MDD) in individuals with type 2...
3.
Gillett A, Jermy B, Lee S, Pain O, Howard D, Hagenaars S, et al.
Genet Epidemiol . 2022 Apr; 46(5-6):219-233. PMID: 35438196
Substantial advances have been made in identifying genetic contributions to depression, but little is known about how the effect of genes can be modulated by the environment, creating a gene-environment...
4.
Pain O, Gillett A, Austin J, Folkersen L, Lewis C
Eur J Hum Genet . 2022 Jan; 30(3):339-348. PMID: 34983942
There is growing interest in the clinical application of polygenic scores as their predictive utility increases for a range of health-related phenotypes. However, providing polygenic score predictions on the absolute...
5.
Gillett A, Vassos E, Lewis C
Hum Hered . 2019 Mar; 83(4):210-224. PMID: 30865946
Objective: Stratified medicine requires models of disease risk incorporating genetic and environmental factors. These may combine estimates from different studies, and the models must be easily updatable when new estimates...
6.
Marschner I, Gillett A
Biostatistics . 2011 Sep; 13(1):179-92. PMID: 21914729
Relative risks (RRs) are generally considered preferable to odds ratios in prospective studies. However, unlike logistic regression for odds ratios, the standard log-binomial model for RR regression does not respect...