Alexandra Bocsik
Overview
Explore the profile of Alexandra Bocsik including associated specialties, affiliations and a list of published articles.
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24
Citations
390
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Recent Articles
1.
Du W, Chen H, Grof I, Lemaitre L, Bocsik A, Perdyan A, et al.
Mol Psychiatry
. 2024 May;
29(11):3590-3598.
PMID: 38816584
As the most prescribed psychotropic drugs in current medical practice, antidepressant drugs (ADs) of the selective serotonin reuptake inhibitor (SSRI) class represent prime candidates for drug repurposing. The mechanisms underlying...
2.
Akel H, Csoka I, Ambrus R, Bocsik A, Grof I, Meszaros M, et al.
Int J Mol Sci
. 2021 Dec;
22(24).
PMID: 34948054
The brain insulin metabolism alteration has been addressed as a pathophysiological factor underlying Alzheimer's disease (AD). Insulin can be beneficial in AD, but its macro-polypeptide nature negatively influences the chances...
3.
Biro T, Bocsik A, Jurisic Dukovski B, Grof I, Lovric J, Csoka I, et al.
Drug Des Devel Ther
. 2021 Feb;
15:351-360.
PMID: 33568896
Background: Optimal transcorneal penetration is necessary for ocular therapy; meanwhile, it is limited by the complex structure and defensive mechanisms of the eye. Antimicrobial stability of topical ophthalmic formulations is...
4.
Grof I, Bocsik A, Harazin A, Santa-Maria A, Vizsnyiczai G, Barna L, et al.
Int J Mol Sci
. 2020 Jun;
21(11).
PMID: 32512832
Clinical and experimental results with inhaled sodium bicarbonate as an adjuvant therapy in cystic fibrosis (CF) are promising due to its mucolytic and bacteriostatic properties, but its direct effect has...
5.
Imre N, Hetenyi A, Szabo E, Bodnar B, Szkalisity A, Grof I, et al.
Adv Sci (Weinh)
. 2020 Feb;
7(4):1902621.
PMID: 32099761
There is a pressing need to develop ways to deliver therapeutic macromolecules to their intracellular targets. Certain viral and bacterial proteins are readily internalized in functional form through lipid raft-mediated/caveolar...
6.
Barna L, Walter F, Harazin A, Bocsik A, Kincses A, Tubak V, et al.
Fluids Barriers CNS
. 2020 Feb;
17(1):5.
PMID: 32036791
Background: Excitotoxicity is a central pathological pathway in many neurological diseases with blood-brain barrier (BBB) dysfunction. Kainate, an exogenous excitotoxin, induces epilepsy and BBB damage in animal models, but the...
7.
Ismail R, Bocsik A, Katona G, Grof I, Deli M, Csoka I
Pharmaceutics
. 2019 Nov;
11(11).
PMID: 31726699
The potential of poly (lactic--glycolic acid) nanoparticles (PLGA NPs) to overcome the intestinal barrier that limits oral liraglutide delivery was evaluated. Liraglutide-loaded PLGA NPs were prepared by the double emulsion...
8.
Bocsik A, Grof I, Kiss L, Otvos F, Zsiros O, Daruka L, et al.
Pharmaceutics
. 2019 Feb;
11(2).
PMID: 30744154
The absorption of drugs is limited by the epithelial barriers of the gastrointestinal tract. One of the strategies to improve drug delivery is the modulation of barrier function by the...
9.
Bartos C, Jojart-Laczkovich O, Katona G, Budai-Szucs M, Ambrus R, Bocsik A, et al.
Drug Des Devel Ther
. 2018 Jun;
12:1567-1580.
PMID: 29910603
Purpose: The article reports a wet milling process, where the planetary ball mill was combined with pearl milling technology to reach nanosize range of meloxicam (Mel; 100-500 nm). The main...
10.
Veszelka S, Toth A, Walter F, Toth A, Grof I, Meszaros M, et al.
Front Mol Neurosci
. 2018 Jun;
11:166.
PMID: 29872378
Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain endothelial cells or immortalized brain endothelial cell...