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Alexander Yaw Debrah

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Articles 40
Citations 815
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Recent Articles
1.
Mensah D, Opoku V, Boateng J, Opoku J, Osei-Mensah J, Gyasi C, et al.
PLoS Negl Trop Dis . 2025 Feb; 19(2):e0012802. PMID: 39903788
Background: The Global Programme to Eliminate Lymphatic Filariasis has made significant gains through mass drug administration (MDA) of Ivermectin/Albendazole. Periodic evaluation of the MDA programme in lymphatic filariasis elimination is...
2.
Debrah L, Klarmann-Schulz U, Osei-Mensah J, Kuehlwein J, Mubarik Y, Nadal J, et al.
Am J Trop Med Hyg . 2024 Oct; 111(4_Suppl):66-82. PMID: 39362213
Filarial lymphedema (LE) remains a significant global problem despite the progress made toward elimination of lymphatic filariasis (LF). In Ghana, the main approach to LF is preventive chemotherapy, but this...
3.
Ngenya A, Klarmann-Schulz U, John W, Korir P, Kamugisha M, Nadal J, et al.
Am J Trop Med Hyg . 2024 Aug; 111(4_Suppl):33-51. PMID: 39191236
Lymphedema, hydrocele, and acute adenolymphangitis (ADL) are chronically disabling consequences in patients with lymphatic filariasis (LF). Provision of morbidity management and disability prevention and concurrent mass drug administration of anthelmintics...
4.
Karunakaran I, Ritter M, Pfarr K, Klarmann-Schulz U, Debrah A, Debrah L, et al.
Front Trop Dis . 2024 Apr; 4. PMID: 38655130
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring disease. The filarial species that are the major...
5.
Debrah L, Gyasi C, Ahiadorme M, Rahamani A, Opoku V, Obeng P, et al.
BMC Infect Dis . 2024 Apr; 24(1):384. PMID: 38589790
Background: Onchocerciasis causes chronic systemic inflammation. Several studies have used markers such as haemato-biochemical indices to predict the occurrence of systemic inflammation. This study assessed the variability and predictability of...
6.
Aku F, Amuasi J, Debrah L, Opoku D, Gmanyami J, Hoerauf A, et al.
BMJ Open . 2023 Dec; 13(12):e074884. PMID: 38070898
Introduction: Countries in the WHO's African region have found community-based surveillance useful in ensuring the effectiveness of the Integrated Disease Surveillance and Response strategy. This approach encourages community participation in...
7.
Mnkai J, Ritter M, Maganga L, Maboko L, Olomi W, Clowes P, et al.
Pathogens . 2023 Mar; 12(3). PMID: 36986309
Background: Infections with are associated with reduced immunity against concomitant infections. Indeed, our previous study described a 2.3-fold increased HIV incidence among individuals with infection, as measured by the circulating...
8.
Mensah D, Debrah L, Gyamfi P, Rahamani A, Opoku V, Boateng J, et al.
PLoS Negl Trop Dis . 2022 Aug; 16(8):e0010129. PMID: 35926012
Background: Lymphatic filariasis (LF) causes chronic morbidity, which usually manifests as lymphedema or hydrocele. Mass drug administration (MDA) began in Kassena Nankana East Municipal (KNEM) and Nabdam, two hotspot districts...
9.
Aniagyei W, Adjei J, Adankwah E, Seyfarth J, Mayatepek E, Antwi Berko D, et al.
Clin Infect Dis . 2022 Jun; 76(3):e1399-e1407. PMID: 35657028
Background: Doxycycline is used for treatment of Mansonella perstans infection. Immune modulatory effects of both M. perstans and doxycycline have been described but long-term implications on host immune response are...
10.
Osei-Boakye F, Addai-Mensah O, Owusu M, Saasi A, Appiah S, Nkansah C, et al.
J Immunoassay Immunochem . 2022 Jan; 43(3):271-287. PMID: 35081871
Tuberculosis constitutes a global emergency as it affects one-third of the world's inhabitants. Although Pulmonary tuberculosis (PTB) is curable, immunological responses to the infection induce several hematological derangements. This study...