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Alexander Y Lau

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Articles 25
Citations 250
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Recent Articles
1.
Zhang X, Hao H, Jin T, Qiu W, Yang H, Xue Q, et al.
Front Immunol . 2023 Nov; 14:1280020. PMID: 38035077
Background: Cerebrospinal fluid oligoclonal band (CSF-OCB) is an established biomarker in diagnosing multiple sclerosis (MS), however, there are no nationwide data on CSF-OCB prevalence and its diagnostic performance in Chinese...
2.
Li S, Tian X, Ip B, Feng X, Ip H, Abrigo J, et al.
J Cereb Blood Flow Metab . 2023 Oct; 44(4):516-526. PMID: 37898104
There may be different mechanisms underlying internal (IBZ) and cortical (CBZ) borderzone infarcts in intracranial atherosclerotic stenosis. In 84 patients with symptomatic, 50-99% atherosclerotic stenosis of M1 middle cerebral artery...
3.
Zheng L, Tian X, Abrigo J, Fang H, Ip B, Liu Y, et al.
Eur Stroke J . 2023 Oct; 9(1):144-153. PMID: 37800871
Introduction: Cerebral small vessel disease (CSVD) commonly exists in patients with symptomatic intracranial atherosclerotic disease (sICAD). We aimed to investigate the associations of hemodynamic features of sICAD lesions with imaging...
4.
Lam Ching W, Li H, Guo J, Yao L, Chau J, Lo S, et al.
BMC Psychiatry . 2023 May; 23(1):314. PMID: 37143014
Background: Patients with post-stroke depression (PSD) usually experience anxiety, hopelessness, and insomnia, which have a negative impact on their daily activities and post-stroke rehabilitation. Acupuncture (AC), as a minimally invasive...
5.
Li H, Lam W, Guo J, Zheng J, Cheung C, Bian Z, et al.
Phytomedicine . 2022 Sep; 106:154442. PMID: 36099653
Background: Stroke is the second leading cause of death worldwide. In Hong Kong, the proportion of deaths caused by cerebrovascular disease accounted for approximately 6.8% of total deaths. Although integrative...
6.
Yuen S, Chua K, Zhong L, Chan K, Chan C, Chan K, et al.
Chin Med . 2022 Jan; 17(1):16. PMID: 35073963
Background: Parkinson's disease (PD) is a prevalent and debilitating condition. Conventional medications cannot control all symptoms and may inflict adverse effects. A survey reported that Chinese herbal medicine (CHM) is...
7.
Shi M, Leng X, Li Y, Chen Z, Cao Y, Chung T, et al.
Stroke Vasc Neurol . 2021 Dec; 7(3):182-189. PMID: 34880113
Objectives: The predisposition of intracranial atherosclerotic disease (ICAD) to East Asians over Caucasians infers a genetic basis which, however, remains largely unknown. Higher prevalence of vascular risk factors (VRFs) in...
8.
Huang S, Wu T, Lau A, Au C, Huang H, Wang X, et al.
iScience . 2021 Nov; 24(11):103247. PMID: 34746708
Low reproducibility in gene expression profiles has been observed in transcriptome studies, and this often limits applying findings to clinical practice. Here, we show time-of-day effects on gene expression and...
9.
Ld Zhong L, Zheng Y, Lau A, Wong N, Yao L, Wu X, et al.
Stroke Vasc Neurol . 2021 Aug; 7(1):77-85. PMID: 34446530
Background: Stroke is a major cause of death or long-term disability worldwide. Many patients with stroke receive integrative therapy consisting of Western medicine (WM) and routine rehabilitation in conjunction with...
10.
Liu C, Zhao L, Fan P, Ko H, Au C, Ng A, et al.
J Clin Neurosci . 2020 Dec; 83:108-111. PMID: 33317883
Background: Serum neurofilament light chain (sNfL) is a promising biomarker for neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS), but there is limited validation data in specific ethnic and...