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Alexander Witte

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Articles 7
Citations 68
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Recent Articles
1.
Schories C, Martus P, Guan T, Kristin Henes J, Witte A, Muller K, et al.
Res Pract Thromb Haemost . 2023 May; 7(4):100165. PMID: 37255851
Background: Platelets express CXCL14, while platelet-derived CXCL14 induces monocyte chemotaxis and exerts an angiostatic effect on endothelial cells. Objectives: This study investigated both platelet surface-associated and circulating levels of CXCL14...
2.
Papatheodorou P, Kindig S, Badilla-Lobo A, Fischer S, Durgun E, Thuraisingam T, et al.
Front Microbiol . 2021 Dec; 12:784856. PMID: 34912322
The intestinal pathogen is a major cause of diarrhea both in hospitals and outpatient in industrialized countries. This bacterium produces two large exotoxins, toxin A (TcdA) and toxin B (TcdB),...
3.
Cebo M, Dittrich K, Fu X, Manke M, Emschermann F, Rheinlaender J, et al.
Blood . 2021 Dec; 139(11):1722-1742. PMID: 34905596
Platelet ACKR3/CXCR7 surface expression is enhanced and influences prognosis in coronary artery disease (CAD) patients, who exhibit a distinct atherothrombotic platelet lipidome. Current investigation validates the potential of ACKR3/CXCR7 in...
4.
Witte A, Rohlfing A, Dannenmann B, Dicenta V, Nasri M, Kolb K, et al.
Cardiovasc Res . 2020 Apr; 117(3):903-917. PMID: 32239134
Aims: Beyond classical roles in thrombosis and haemostasis, it becomes increasingly clear that platelets contribute as key players to inflammatory processes. The involvement of platelets in these processes is often...
5.
Papatheodorou P, Song S, Lopez-Urena D, Witte A, Marques F, Ost G, et al.
FASEB J . 2018 Dec; 33(4):4883-4892. PMID: 30592645
Clostridium difficile is associated with antibiotic-associated diarrhea and pseudomembranous colitis in humans. Its 2 major toxins, toxins A and B, enter host cells and inactivate GTPases of the Ras homologue/rat...
6.
Sang H, Witte A, Jacobs J, Chang H, Wang J, Roth M, et al.
Front Microbiol . 2018 Oct; 9:2335. PMID: 30327645
The succinate dehydrogenase inhibitor (SDHI) fungicide, fluopyram, is used as a soybean seed treatment to manage , the casual agent of sudden death syndrome (SDS). More recently, other species within...
7.
Witte A, Chatterjee M, Lang F, Gawaz M
Cell Physiol Biochem . 2017 Mar; 41(4):1684-1696. PMID: 28359053
Objective: Platelets are a major source of chemokines. Here, we demonstrate for the first time that platelets express significant amounts of CXCL14 and disclose powerful effects of platelet-derived CXCL14 on...