Alexander W Alund
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Explore the profile of Alexander W Alund including associated specialties, affiliations and a list of published articles.
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12
Citations
80
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Recent Articles
1.
Janganati V, Salazar P, Parks B, Gorman G, Prather P, Peterson E, et al.
Front Pharmacol
. 2023 May;
14:1123261.
PMID: 37229250
An active metabolite of buprenorphine (), called norbuprenorphine (), is implicated in neonatal opioid withdrawal syndrome when BUP is taken during pregnancy. Therefore, reducing or eliminating metabolism of BUP to...
2.
Du H, Pan B, Alund A, Yan J, Chen Y, Robison T, et al.
Arch Toxicol
. 2023 May;
97(8):2261-2272.
PMID: 37209179
In contrast to somatic mutations, mutations in germ cells affect every cell of any organism derived from the germ cell and therefore are related to numerous genetic diseases. However, there...
3.
Miranda J, Alund A, Yan J, McKinzie P, Dobrovolsky V, Revollo J
Environ Mol Mutagen
. 2022 Feb;
63(2):68-75.
PMID: 35224786
Many conventional genetic toxicology assays require specialized cell cultures or animals and can only detect mutations that inactivate the function of a reporter gene. These limitations make such assays incompatible...
4.
Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells
Pan B, Kaldhone P, Alund A, Du H, Guo X, Yan J, et al.
Nanotoxicology
. 2021 Mar;
15(3):418-432.
PMID: 33710943
The increasing medical and food applications of silver nanoparticles (AgNPs) raise concerns about their safety, including the potential health consequences of human exposure. Previous studies found that AgNPs were negative...
5.
Ronis M, Watt J, Pulliam C, Williams A, Alund A, Haque E, et al.
Arch Toxicol
. 2019 Dec;
94(2):389-399.
PMID: 31820026
Skeletal toxicity has been reported following exposure to polychlorinated biphenyl (PCB) mixtures. However, molecular mechanisms remain poorly understood. We exposed groups of male 4-5-week-old Sprague-Dawley rats to 3,3', 4, 4',...
6.
Chen J, Wankhade U, Alund A, Blackburn M, Shankar K, Lazarenko O
JBMR Plus
. 2019 Nov;
3(9):e10201.
PMID: 31667457
Phenolic acids (PAs) are metabolites derived from polyphenolic compounds found in fruits and vegetables resulting from the actions of gut bacteria. Previously, we reported that the levels of seven individual...
7.
Griffin B, Caperton C, Russell L, Cabanlong C, Wilson C, Urquhart K, et al.
J Pharmacol Exp Ther
. 2019 Apr;
370(1):9-17.
PMID: 31028107
Buprenorphine is the preferred treatment of opioid use disorder during pregnancy but can cause fetal opioid dependence and neonatal opioid withdrawal syndrome (NOWS). Notably, withdrawal severity is independent of maternal...
8.
Chen J, Lazarenko O, Zhao H, Alund A, Shankar K
J Endocrinol
. 2018 Oct;
239(1):33–47.
PMID: 30307152
Intrauterine or early postnatal high-fat diet (HFD) has substantial influences on adult offspring health; however, studies of HFD-induced maternal obesity on regulation of adult offspring bone formation are sparse. Here,...
9.
Watt J, Alund A, Pulliam C, Mercer K, Suva L, Chen J, et al.
J Pharmacol Exp Ther
. 2018 Apr;
366(1):46-57.
PMID: 29653963
Chronic alcohol consumption increases bone resorption and decreases bone formation. A major component of ethanol (EtOH) pathology in bone is the generation of excess reactive oxygen species (ROS). The ROS-generating...
10.
Alund A, Mercer K, Pulliam C, Suva L, Chen J, Badger T, et al.
Alcohol Clin Exp Res
. 2016 Dec;
41(1):46-56.
PMID: 27987315
Background: Chronic alcohol consumption leads to increased fracture risk and an elevated risk of osteoporosis by decreasing bone accrual through increasing osteoclast activity and decreasing osteoblast activity. We have shown...