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Alexander V Predeus

Explore the profile of Alexander V Predeus including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 532
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Recent Articles
1.
Ivanova O, Predeus A, Sorokina M, Ignatieva E, Bobkov D, Sukhareva K, et al.
Sci Rep . 2025 Feb; 15(1):5358. PMID: 39948343
LMNA mutations causing classical familial partial lipodystrophy of Dunnigan type (FPLD2) usually affect residue R482. FPLD is a severe metabolic disorder that often leads to cardiovascular and skeletal muscle complications....
2.
Li Y, Pulford C, Diaz P, Perez-Sepulveda B, Duarte C, Predeus A, et al.
PLoS Negl Trop Dis . 2025 Jan; 19(1):e0012801. PMID: 39874387
Salmonella enterica serovar Typhimurium is a prevalent food-borne pathogen that is usually associated with gastroenteritis infection. S. Typhimurium is also a major cause of bloodstream infections in sub-Saharan Africa, and...
3.
To K, Fei L, Pett J, Roberts K, Blain R, Polanski K, et al.
Nature . 2024 Nov; 635(8039):657-667. PMID: 39567793
Human embryonic bone and joint formation is determined by coordinated differentiation of progenitors in the nascent skeleton. The cell states, epigenetic processes and key regulatory factors that underlie lineage commitment...
4.
Yayon N, Kedlian V, Boehme L, Suo C, Wachter B, Beuschel R, et al.
Nature . 2024 Nov; 635(8039):708-718. PMID: 39567784
T cells develop from circulating precursor cells, which enter the thymus and migrate through specialized subcompartments that support their maturation and selection. In humans, this process starts in early fetal...
5.
Oliver A, Huang N, Bartolome-Casado R, Li R, Koplev S, Nilsen H, et al.
Nature . 2024 Nov; 635(8039):699-707. PMID: 39567783
The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and barrier immunity. Advances in genomics and a surge in gastrointestinal diseases has fuelled efforts to catalogue cells...
6.
Barbitoff Y, Khmelkova D, Pomerantseva E, Slepchenkov A, Zubashenko N, Mironova I, et al.
Natl Sci Rev . 2024 Nov; 11(10):nwae326. PMID: 39498263
Population allele frequency is crucially important for accurate interpretation of known and novel variants in medical genetics. Recently, several large allele frequency databases, such as the Genome Aggregation Database (gnomAD),...
7.
Klein J, Predeus A, Greissl A, Clark-Herrera M, Cruz E, Cundiff J, et al.
Infect Immun . 2024 Sep; 92(10):e0031424. PMID: 39254346
is a Gram-negative bacterium found in various water and land environments and organisms, including insects and mammals. Some strains encode gene homologs of virulence factors found in pathogenic Enterobacterales members,...
8.
Yu X, Xie H, Li Y, Liu M, Hou R, Predeus A, et al.
mBio . 2024 Jun; 15(7):e0112824. PMID: 38904384
Importance: In , the injectisome machinery encoded by pathogenicity island 2 (SPI-2) is conserved among the five subspecies and delivers proteins (effectors) into host cells, which are required for virulence....
9.
Klein J, Predeus A, Greissl A, Clark-Herrera M, Cruz E, Cundiff J, et al.
bioRxiv . 2024 Jun; PMID: 38895369
is a Gram-negative bacterium found in a wide variety of water and land environments and organisms. It has been isolated as part of the gut microbiome of animals and insects,...
10.
Easter Q, Fernandes Matuck B, Beldorati Stark G, Worth C, Predeus A, Fremin B, et al.
Nat Commun . 2024 Jun; 15(1):5016. PMID: 38876998
Periodontitis affects billions of people worldwide. To address relationships of periodontal niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA sequencing (scRNAseq) atlas of human periodontium...