Alexander V Birk
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Explore the profile of Alexander V Birk including associated specialties, affiliations and a list of published articles.
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8
Citations
339
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Recent Articles
1.
Mitchell W, Tamucci J, Ng E, Liu S, Birk A, Szeto H, et al.
Elife
. 2022 Aug;
11.
PMID: 35913044
Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with alternating cationic and aromatic residues such...
2.
Zhu X, Aoyama E, Birk A, Onasanya O, Carr W, Mourokh L, et al.
Biochim Biophys Acta Bioenerg
. 2020 Jul;
1861(11):148262.
PMID: 32673675
Background: The electrochemical and spectroscopic investigation of bacterial electron-transfer proteins stabilized on solid state electrodes has provided an effective approach for functional respiratory enzyme studies. Methods: We assess the biocompatibility...
3.
Disruption of cytochrome c heme coordination is responsible for mitochondrial injury during ischemia
Birk A, Chao W, Liu S, Soong Y, Szeto H
Biochim Biophys Acta
. 2015 Jun;
1847(10):1075-84.
PMID: 26071084
Background: It was recently suggested that electron flow into cyt c, coupled with ROS generation, oxidizes cyt c Met(80) to Met(80) sulfoxide (Met-O) in isolated hearts after ischemia-reperfusion, and converts...
4.
Szeto H, Liu S, Soong Y, Birk A
Am J Physiol Renal Physiol
. 2014 Oct;
308(1):F11-21.
PMID: 25339695
Ischemia time during partial nephrectomy is strongly associated with acute and chronic renal injury. ATP depletion during warm ischemia inhibits ATP-dependent processes, resulting in cell swelling, cytoskeletal breakdown, and cell...
5.
Birk A, Liu S, Soong Y, Mills W, Singh P, Warren J, et al.
J Am Soc Nephrol
. 2013 Jul;
24(8):1250-61.
PMID: 23813215
Ischemia causes AKI as a result of ATP depletion, and rapid recovery of ATP on reperfusion is important to minimize tissue damage. ATP recovery is often delayed, however, because ischemia...
6.
Zhang X, Mason P, Dubovi E, Xu X, Bourne N, Renshaw R, et al.
Antiviral Res
. 2009 Jun;
83(1):21-7.
PMID: 19501253
The aminoglycoside, geneticin (G418), was recently shown to have antiviral activity against bovine viral diarrhea virus (BVDV). Since BVDV, dengue virus (DENV) and yellow fever virus (YFV) all belong to...
7.
Birk A, Dubovi E, Zhang X, Szeto H
Antivir Chem Chemother
. 2008 Jul;
19(1):33-40.
PMID: 18610556
Background: Aminoglycoside G418 is commonly used to generate stable replicons for RNA viruses, such as hepatitis C virus, West Nile virus, and bovine viral diarrhoea virus (BVDV). This precludes testing...
8.
Birk A, Dubovi E, Cohen-Gould L, Donis R, Szeto H
Virus Res
. 2007 Dec;
132(1-2):76-85.
PMID: 18054406
Bovine Viral Diarrhea Virus (BVDV) is a positive sense, single-stranded RNA virus which exhibits two biotypes in standard cell culture systems. The cytopathic strains of this virus (cpBVDV) induce dramatic...