Alexander Tischer
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Explore the profile of Alexander Tischer including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
1.
Tischer A, Moon-Tasson L, Auton M
Thromb J
. 2025 Jan;
23(1):3.
PMID: 39825354
The REAADS VWF activity assay is often assumed to be specific for the A1 domain, the portion of VWF that binds platelet GPIbα. We tested this assay on the A1A2A3...
2.
Tischer A, Moon-Tasson L, Auton M
J Thromb Haemost
. 2025 Jan;
PMID: 39756657
Background: Genetically determined amino acid substitutions in the platelet adhesive A1 domain alter von Willebrand factor's (VWF) platelet agglutination competence, resulting in both gain- (type 2B) and loss-of-function (type 2M)...
3.
Machha V, Tischer A, Moon-Tasson L, Tange J, Santiago-Davis A, Pruthi R, et al.
NAR Mol Med
. 2024 Dec;
1(4):ugae021.
PMID: 39719968
The A1 domain in Von Willebrand Factor (VWF) initiates coagulation through binding to platelet glycoprotein GPIbα receptors. Von Willebrand Disease (VWD)-Mutations in A1 that either impair (type 2M) or enhance...
4.
Sumerskii I, Bohmdorfer S, Tsetsgee O, Sulaeva I, Khaliliyan H, Musl O, et al.
ChemSusChem
. 2024 Jan;
17(10):e202301840.
PMID: 38240610
We present an approach to overcome the challenges associated with the increasing demand of high-throughput characterization of technical lignins, a key resource in emerging bioeconomies. Our approach offers a resort...
5.
Misra P, Tischer A, Lampe L, Pierluissi-Ruiz V, Dick C, Bragantini B, et al.
Biochim Biophys Acta Proteins Proteom
. 2024 Jan;
1872(3):140993.
PMID: 38169170
Immunoglobulin light chain (AL) amyloidosis involves the deposition of insoluble monoclonal AL protein fibrils in the extracellular space of different organs leading to dysfunction and death. Development of methods to...
6.
7.
Putzenlechner B, Koal P, Kappas M, Low M, Mundhenk P, Tischer A, et al.
Sci Total Environ
. 2023 Apr;
880:163114.
PMID: 37011694
Prolonged drought and susceptibility to biotic stressors induced an extensive calamity in Norway spruce (Picea abies (L.) Karst.) and widespread crown defoliation in European beech (Fagus sylvatica L.) in Central...
8.
Tischer A, Moon-Tasson L, Auton M
Blood
. 2023 Jan;
141(12):1469-1473.
PMID: 36603190
A redox autoinhibitory mechanism has previously been proposed, in which the reduced state of the vicinal disulfide bond in the von Willebrand factor (VWF) A2 domain allows A2 to bind...
9.
Meyer U, Tischer A, Freitag M, Klaus V, Kleinebecker T, Oelmann Y, et al.
Sci Total Environ
. 2022 May;
836:155748.
PMID: 35526633
Grassland ecosystems provide important ecosystem services such as nutrient cycling and primary production that are affected by land-use intensity. To assess the effects of land-use intensity, operational and sensitive ecological...
10.
Sustained, complete response to pexidartinib in a patient with CSF1R-mutated Erdheim-Chester disease
Abeykoon J, Lasho T, Dasari S, Rech K, Ranatunga W, Manske M, et al.
Am J Hematol
. 2022 Jan;
97(3):293-302.
PMID: 34978715
Erdheim-Chester disease (ECD) is a histiocytic neoplasm that predominantly harbors mitogen-activated protein kinase (MAPK) pathway variants. MAPK inhibitors typically are effective treatments, but mutations outside the MAPK pathway, such as...