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Alexander Schafer

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Articles 34
Citations 693
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Recent Articles
11.
Schafer A, Vetsova V, Schneider E, Kappes M, Seitz M, Daumann L, et al.
J Am Soc Mass Spectrom . 2022 Mar; 33(4):722-730. PMID: 35300493
Lanthanide-dependent enzymes and their biomimetic complexes have arisen as an interesting target of research in the past decade. These enzymes, specifically, pyrroloquinoline quinone (PQQ)-bearing methanol dehydrogenases, efficiently convert alcohols to...
12.
Schafer A, Franzoni G, Netherton C, Hartmann L, Blome S, Blohm U
Pathogens . 2022 Feb; 11(2). PMID: 35215216
African swine fever virus (ASFV) remains a threat to global pig populations. Infections with ASFV lead to a hemorrhagic disease with up to 100% lethality in Eurasian domestic and wild...
13.
Kaplonek P, Yao L, Reppe K, Voss F, Kohler T, Ebner F, et al.
Vaccine . 2022 Jan; 40(7):1038-1046. PMID: 35033388
Streptococcus pneumoniae (S. pneumoniae)infections are the leading cause of child mortality globally. Currentvaccines fail to induceaprotective immune response towards a conserved part of the pathogen,resulting in newserotypescausing disease. Therefore, new...
14.
Sehl-Ewert J, Schwaiger T, Schafer A, Holper J, Klupp B, Teifke J, et al.
Brain Pathol . 2021 Oct; 32(3):e13031. PMID: 34709694
Herpes simplex encephalitis (HSE) is one of the most serious diseases of the nervous system in humans. However, its pathogenesis is still only poorly understood. Although several mouse models of...
15.
Cuypers F, Schafer A, Skorka S, Surabhi S, Tolken L, Paulikat A, et al.
Sci Rep . 2021 Oct; 11(1):20609. PMID: 34663857
Seasonal Influenza A virus (IAV) infections can promote dissemination of upper respiratory tract commensals such as Streptococcus pneumoniae to the lower respiratory tract resulting in severe life-threatening pneumonia. Here, we...
16.
Blaurock C, Blohm U, Luttermann C, Holzerland J, Scheibner D, Schafer A, et al.
Emerg Microbes Infect . 2021 Aug; 10(1):1760-1776. PMID: 34420477
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1...
17.
Vetsova V, Fisher K, Lumpe H, Schafer A, Schneider E, Weis P, et al.
Chemistry . 2021 Apr; 27(39):10087-10098. PMID: 33872420
Understanding the role of metal ions in biology can lead to the development of new catalysts for several industrially important transformations. Lanthanides are the most recent group of metal ions...
18.
Schafer A, Zani L, Pikalo J, Huhr J, Sehl J, Mettenleiter T, et al.
Transbound Emerg Dis . 2021 Feb; 68(5):2733-2749. PMID: 33630409
Infection with African swine fever virus (ASFV) causes a highly lethal haemorrhagic disease in domestic and Eurasian wild pigs. Thus, it is a major threat to pig populations worldwide and...
19.
Schafer A, Haenig B, Erupathil J, Strickner P, Sabato D, Welford R, et al.
Oncogene . 2021 Jan; 40(9):1659-1673. PMID: 33500549
The clinical benefit of MAPK pathway inhibition in melanoma patients carrying BRAF mutations is temporal. After the initial response to treatment, the majority of tumors will develop resistance and patients...
20.
Mostafa A, Blaurock C, Scheibner D, Muller C, Blohm U, Schafer A, et al.
Virus Evol . 2020 Dec; 6(2):veaa077. PMID: 33343923
The unprecedented spread of H5N8- and H9N2-subtype avian influenza virus (AIV) in birds across Asia, Europe, Africa, and North America poses a serious public health threat with a permanent risk...